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Difference between revisions of "Gastrointestinal tract polyps"
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Gastrointestinal tract polyps (view source)
Revision as of 03:39, 15 November 2012
, 03:39, 15 November 2012→Hamartomatous polyps
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*The above exactly mirrors the Canadian consensus.<ref name=driman>{{cite journal | last1 = Driman | first1 = DK. | last2 = Marcus | first2 = VA. | last3 = Hilsden | first3 = RJ | last4 = Owen | first4 = DA |title=Pathologic reporting of colorectal polyps: pan-Canadian consensus guidelines |journal=Canadian Journal of Pathology |volume=4 |issue=3 |pages=81-90 |year=2012 |month= |pmid= |doi= |url= }}</ref> | *The above exactly mirrors the Canadian consensus.<ref name=driman>{{cite journal | last1 = Driman | first1 = DK. | last2 = Marcus | first2 = VA. | last3 = Hilsden | first3 = RJ | last4 = Owen | first4 = DA |title=Pathologic reporting of colorectal polyps: pan-Canadian consensus guidelines |journal=Canadian Journal of Pathology |volume=4 |issue=3 |pages=81-90 |year=2012 |month= |pmid= |doi= |url= }}</ref> | ||
=Malignant polyps= | |||
==Colorectal adenocarcinoma== | |||
{{Main|Colorectal adenocarcinoma}} | |||
===General=== | |||
*May be a challenging diagnosis. | |||
===Microscopic=== | |||
Features:<ref name=pmid22827760>{{Cite journal | last1 = Kimura | first1 = R. | last2 = Fujimori | first2 = T. | last3 = Ichikawa | first3 = K. | last4 = Ajioka | first4 = Y. | last5 = Ueno | first5 = H. | last6 = Ohkura | first6 = Y. | last7 = Kashida | first7 = H. | last8 = Togashi | first8 = K. | last9 = Yao | first9 = T. | title = Desmoplastic reaction in biopsy specimens of early colorectal cancer: a Japanese prospective multicenter study. | journal = Pathol Int | volume = 62 | issue = 8 | pages = 525-31 | month = Aug | year = 2012 | doi = 10.1111/j.1440-1827.2012.02840.x | PMID = 22827760 }}</ref> | |||
*Desmoplastic response - '''key feature'''. | |||
*Nuclear changes seen in adenomatous polyps. | |||
**Enlarged. | |||
**Chromatin hyperchromatic ''or'' vesicular. | |||
**Round-shap ''or'' cigar-shaped and pseudostratified. | |||
*Architectural changes - usually those of high-grade dysplasia: | |||
**Cribriforming. | |||
**Papillary tufting. | |||
**Budding. | |||
=Hamartomatous polyps= | =Hamartomatous polyps= | ||