Difference between revisions of "An introduction to head and neck pathology"

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An introduction to head and neck pathology (view source)

Revision as of 14:09, 12 November 2012

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→‎Hairy leukoplakia: mv to oral pathology
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*CD31 +ve.
*CD31 +ve.
*Factor VIII +ve.
*Factor VIII +ve.
==Hairy leukoplakia==
===General===
Features:<ref name=Ref_PBoD777>{{Ref PBoD|777}}</ref>
*Oral lesion.
**Often on [[tongue]].
*Caused by [[EBV]].<ref name=pmid2169222>{{Cite journal  | last1 = Kanitakis | first1 = J. | last2 = Zambruno | first2 = G. | last3 = Marchand | first3 = C. | last4 = Perret-Liaudet | first4 = P. | last5 = Hermier | first5 = C. | last6 = Thivolet | first6 = J. | title = [Oral hairy leukoplakia in AIDS. Histologic and ultrastructural study of 8 cases]. | journal = Ann Dermatol Venereol | volume = 117 | issue = 5 | pages = 345-53 | month =  | year = 1990 | doi =  | PMID = 2169222 }}</ref>
**May be seen in the context of a [[HIV]]-infection.<ref>{{Cite journal  | last1 = Itin | first1 = PH. | last2 = Lautenschlager | first2 = S. | title = Viral lesions of the mouth in HIV-infected patients. | journal = Dermatology | volume = 194 | issue = 1 | pages = 1-7 | month =  | year = 1997 | doi =  | PMID = 9031782 }}</ref>
===Gross===
*White confluent patches (icing sugar) - usu. tongue.
Images:
*[http://bestpractice.bmj.com/best-practice/monograph/621/resources/image/bp/6.html Hairy leukoplakia (bestpractise.bmj.com)].
*[http://hardinmd.lib.uiowa.edu/cdc/6061.html Hairy leukoplakia (uiowa.edu)].
===Microscopic===
Features:<ref>URL: [http://www.pathologyoutlines.com/oralcavity.html#hairyleukoplakia http://www.pathologyoutlines.com/oralcavity.html#hairyleukoplakia].</ref>
*Hyperkeratosis (thicker stratum corneum).<ref>URL: [http://www.emedicine.com/asp/dictionary.asp?keyword=hyperkeratosis http://www.emedicine.com/asp/dictionary.asp?keyword=hyperkeratosis].</ref>
*Acanthosis (thicker stratum spinosum).<ref>URL: [http://www.emedicine.com/asp/dictionary.asp?keyword=acanthosis http://www.emedicine.com/asp/dictionary.asp?keyword=acanthosis].</ref>
*"Balloon cells" in upper stratum spinosum - perinuclear clearing.


==Plummer-Vinson syndrome==
==Plummer-Vinson syndrome==
Michael
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