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===General=== | ===General=== | ||
*Considered the precursor lesion for tubal [[serous carcinoma]].<ref name=pmid17117391>{{Cite journal | last1 = Lee | first1 = Y. | last2 = Miron | first2 = A. | last3 = Drapkin | first3 = R. | last4 = Nucci | first4 = MR. | last5 = Medeiros | first5 = F. | last6 = Saleemuddin | first6 = A. | last7 = Garber | first7 = J. | last8 = Birch | first8 = C. | last9 = Mou | first9 = H. | title = A candidate precursor to serous carcinoma that originates in the distal fallopian tube. | journal = J Pathol | volume = 211 | issue = 1 | pages = 26-35 | month = Jan | year = 2007 | doi = 10.1002/path.2091 | PMID = 17117391 }}</ref> | *Considered the precursor lesion for tubal [[serous carcinoma]].<ref name=pmid17117391>{{Cite journal | last1 = Lee | first1 = Y. | last2 = Miron | first2 = A. | last3 = Drapkin | first3 = R. | last4 = Nucci | first4 = MR. | last5 = Medeiros | first5 = F. | last6 = Saleemuddin | first6 = A. | last7 = Garber | first7 = J. | last8 = Birch | first8 = C. | last9 = Mou | first9 = H. | title = A candidate precursor to serous carcinoma that originates in the distal fallopian tube. | journal = J Pathol | volume = 211 | issue = 1 | pages = 26-35 | month = Jan | year = 2007 | doi = 10.1002/path.2091 | PMID = 17117391 }}</ref> | ||
===Gross=== | |||
*Not apparent on gross. | |||
*Usually at the fimbriated end of the tube. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid20228782/> | Features:<ref name=pmid20228782/> | ||
*Discrete papillary growth. | *Discrete papillary growth - low power. | ||
*Formal criteria - need 3 or more: | |||
*#Atypical chromatin pattern. | |||
*#Nuclear enlargement. | |||
*#Nuclear pleomorphism. | |||
*#Nuclear moulding. | |||
*#Loss of nuclear polarity ''or'' epithelial stratification. | |||
Image: | Image: |
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