48,830
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m (→Bowenoid) |
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Line 242: | Line 242: | ||
</pre> | </pre> | ||
====Bowenoid==== | |||
<pre> | <pre> | ||
SKIN LESION, RIGHT DISTAL FOREARM, BIOPSY: | SKIN LESION, RIGHT DISTAL FOREARM, BIOPSY: | ||
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- NEGATIVE FOR MALIGNANCY. | - NEGATIVE FOR MALIGNANCY. | ||
</pre> | </pre> | ||
====Micro==== | ====Micro==== | ||
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=====Bowenoid===== | =====Bowenoid===== | ||
The sections show skin with epidermal nuclear enlargement and hyperchromasia with irregular nuclear palisading. The lesion involves the full thickness of the epidermis; however, it spares follicular epithelium. Proliferative activity is present. Hyperkeratosis and parakeratosis is present. A granular layer is present. | The sections show skin with epidermal nuclear enlargement and hyperchromasia with irregular nuclear palisading. The lesion involves the full thickness of the epidermis; however, it spares follicular epithelium. Proliferative activity is present. Hyperkeratosis and parakeratosis is present. A granular layer is present. The dermal-epidermal interface is sharply-demarcated. There is focal inflammation at the interface. Extensive solar elastosis is present. | ||
There is no clefting of the lesion from the surrounding stroma. Intercellular bridges are identified. | There is no clefting of the lesion from the surrounding stroma. Intercellular bridges are identified. |
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