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The '''ovary''' has a wealth of [[pathology]]. It has benign tumours and malignant ones. It is a significant part of [[gynecologic pathology]]. | The '''ovary''' has a wealth of [[pathology]]. It has benign tumours and malignant ones. It is a significant part of [[gynecologic pathology]]. | ||
=Normal ovary= | |||
*Corpora albicans - pale/white body with lobulated contour. | *Corpora albicans - pale/white body with lobulated contour. | ||
**Involuted corpus luteum. | **Involuted corpus luteum. | ||
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**If the cells have a round morphology... think about [[endometriosis]]. | **If the cells have a round morphology... think about [[endometriosis]]. | ||
Images: | ===Images=== | ||
www: | |||
*[http://media.photobucket.com/image/ovary%20histology/lovesthesunset/anatomy%20and%20physiology/ovarycorpusluteum.jpg Ovarian stroma (photobucket.com)]. | *[http://media.photobucket.com/image/ovary%20histology/lovesthesunset/anatomy%20and%20physiology/ovarycorpusluteum.jpg Ovarian stroma (photobucket.com)]. | ||
<gallery> | |||
Image:Corpus_albicans.JPG| Corpus albicans. (WC) | |||
</gallery> | |||
== | =Cysts - overview= | ||
General | ==General== | ||
*Very common. | *Very common. | ||
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*Endometrioma (see [[endometriosis]]). | *Endometrioma (see [[endometriosis]]). | ||
*Simple cyst. | *Simple cyst. | ||
*[[Corpus luteum cyst]]. | |||
*Cancerous cyst (see [[ovarian cancer]]). | *Cancerous cyst (see [[ovarian cancer]]). | ||
Notes | Notes: | ||
*Epithelium is often lost in processing - may make interpretation challenging | *Epithelium is often lost in processing - may make interpretation challenging | ||
*Ovarian surface epithelium (previously call ''germinal epithelium'') - covers the ovary | *Ovarian surface epithelium (previously call ''germinal epithelium'') - covers the ovary | ||
**Cuboidal/flat epithelium.<ref>{{cite journal |author=Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC |title=Ovarian surface epithelium: biology, endocrinology, and pathology |journal=Endocr. Rev. |volume=22 |issue=2 |pages=255–88 |year=2001 |month=April |pmid=11294827 |doi= |url=http://edrv.endojournals.org/cgi/pmidlookup?view=long&pmid=11294827}}</ref> | **Cuboidal/flat epithelium.<ref>{{cite journal |author=Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC |title=Ovarian surface epithelium: biology, endocrinology, and pathology |journal=Endocr. Rev. |volume=22 |issue=2 |pages=255–88 |year=2001 |month=April |pmid=11294827 |doi= |url=http://edrv.endojournals.org/cgi/pmidlookup?view=long&pmid=11294827}}</ref> | ||
**Has ovarian stroma underneath. | **Has ovarian stroma underneath. | ||
** | **Hobnail morphology (free surface larger than basement membrane surface).<ref>ALS. 5 February 2009.</ref> | ||
Ovarian surface vs. mesothelium: | Ovarian surface vs. mesothelium: | ||
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*Image: [http://internetattitude.com/bioimage/OldSlides/bio231histo800x600/Mesothelium%20Simple%20Squamous%20x440.JPG mesothelium] - internetattitude.com. | *Image: [http://internetattitude.com/bioimage/OldSlides/bio231histo800x600/Mesothelium%20Simple%20Squamous%20x440.JPG mesothelium] - internetattitude.com. | ||
=Specific benign diagnoses= | |||
==Endometriosis== | ==Endometriosis== | ||
{{main|Endometriosis}} | {{main|Endometriosis}} | ||
== | ==Corpus luteum cyst== | ||
===General=== | |||
*Normal in childbearing age women. | |||
===Gross=== | |||
*Classically yellow. | |||
===Microscopic=== | |||
Features: | |||
*Pseudocyst lined by stratified, pale staining (luteinized) cells. | |||
*+/-Hemorrhagic centre. | |||
Images: | |||
*[http://commons.wikimedia.org/wiki/File:Luteinized_follicular_cyst.jpg Luteinized cells in a follicular cyst (WC)]. | |||
*[http://php.med.unsw.edu.au/embryology/index.php?title=File:Ovary_corpus_luteum.jpg Corpus luteum (unsw.edu.au)]. | |||
==Benign mesothelial inclusion cyst== | ==Benign mesothelial inclusion cyst== | ||
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*[[AKA]] ''[[peritoneal inclusion cyst]]''.{{fact}} | *[[AKA]] ''[[peritoneal inclusion cyst]]''.{{fact}} | ||
*[[AKA]] ''cortical inclusion cyst''.<ref name=pmid11207821>{{Cite journal | last1 = Feeley | first1 = KM. | last2 = Wells | first2 = M. | title = Precursor lesions of ovarian epithelial malignancy. | journal = Histopathology | volume = 38 | issue = 2 | pages = 87-95 | month = Feb | year = 2001 | doi = | PMID = 11207821 }}</ref>{{fact}} | *[[AKA]] ''cortical inclusion cyst''.<ref name=pmid11207821>{{Cite journal | last1 = Feeley | first1 = KM. | last2 = Wells | first2 = M. | title = Precursor lesions of ovarian epithelial malignancy. | journal = Histopathology | volume = 38 | issue = 2 | pages = 87-95 | month = Feb | year = 2001 | doi = | PMID = 11207821 }}</ref>{{fact}} | ||
*[[AKA]] ''surface epithelial inclusion cyst''. | |||
===General=== | ===General=== | ||
*May be found incidentally, e.g. during C-section. | *May be found incidentally, e.g. during C-section. | ||
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DDx: | DDx: | ||
*[[Serous cystadenoma of the ovary]]. | *[[Serous cystadenoma of the ovary]] - must be >=1 cm.<ref name=Ref_GP384>{{Ref GP|384}}</ref> | ||
Image: | Image: | ||
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- BENIGN CORTICAL INCLUSION CYST. | - BENIGN CORTICAL INCLUSION CYST. | ||
</pre> | </pre> | ||
==Ovarian infarct== | |||
{{Main|Ovarian infarct}} | |||
==Pregnancy luteoma== | ==Pregnancy luteoma== | ||
*[[AKA]] ''luteoma of [[pregnancy]]''. | *[[AKA]] ''luteoma of [[pregnancy]]''. | ||
{{Main|Pregnancy luteoma}} | |||
=Ovarian tumours= | |||
{{main|Ovarian tumours}} | |||
For a ''very'' brief overview of gynecologic tumours see: ''[[Gynecologic pathology]]''. | |||
=See also= | |||
*[[Gynecologic pathology]]. | *[[Gynecologic pathology]]. | ||
*[[Testis]]. | *[[Testis]]. | ||
=References= | |||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Gynecologic pathology]] | [[Category:Gynecologic pathology]] |
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