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Difference between revisions of "Endometrium"
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→Benign endometrial polyp
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*May be a cause of menorrhagia (heavy & long menses). | *May be a cause of menorrhagia (heavy & long menses). | ||
===Gross=== | |||
*Polypoid mass in the endometrial cavity. | |||
Gross DDx: | |||
*[[Secretory phase endometrium]].<ref name=pmid16873562/> | |||
*Pedunculated [[uterine leiomyoma|leiomyoma]]. | |||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref> | Features - diagnostic criteria:<ref name=pmid16873562>{{Cite journal | last1 = McCluggage | first1 = WG. | title = My approach to the interpretation of endometrial biopsies and curettings. | journal = J Clin Pathol | volume = 59 | issue = 8 | pages = 801-12 | month = Aug | year = 2006 | doi = 10.1136/jcp.2005.029702 | PMID = 16873562 | PMC = 1860448 }}</ref> | ||
#Large blood vessels (muscular) - '''key feature'''. | #Large blood vessels (muscular) - '''key feature'''. | ||
#Fibrotic stroma - '''key feature'''. | #Fibrotic stroma - '''key feature'''. | ||
#Polypoid shape - epithelium on three sides. | #Polypoid shape - epithelium on three sides. | ||
#*May not be seen... as polyp is fragmented on removal. | #*May not be seen... as polyp is fragmented on removal. | ||
Glandular changes common:<ref name=pmid16873562/> | |||
*Endometrial glands may be out of phase with surrounding [[endometrium]]. | |||
**Often proliferative. | |||
*+/-Cystic dilation of glands/unusual shapes. | |||
*+/-Focal crowding. | |||
Notes: | Notes: | ||
#Apparently benign polyps should be examined closely at the surface for in situ & invasive malignancies. | #Apparently benign polyps should be examined closely at the surface for in situ & invasive malignancies. | ||
# | #Stroma often cellular. | ||
DDx: | |||
*[[Adenofibroma]]. | *[[Adenofibroma]]. | ||
*[[Cervical polyp]]. | *[[Cervical polyp]] - have endocervical mucosa. | ||
* | *Lower uterine segment - have endocervical epithelium and lack the thick-walled blood vessels.<ref name=pmid16873562/> | ||
==Disordered proliferative endometrium== | ==Disordered proliferative endometrium== | ||