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Difference between revisions of "Endometrium"
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→Microscopic: tweak
(→Proliferative phase endometrium: +abbrev. ppe) |
(→Microscopic: tweak) |
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features:<ref name=pmid16873562/> | ||
*Glands: | *Glands: | ||
**Straight, tubular, composed of tall pseudostratified columnar cells - '''key feature'''. | **Straight, tubular, composed of tall pseudostratified columnar cells - '''key feature'''. | ||
**Mitotic figures - '''key feature'''. | **Mitotic figures - '''key feature'''. † | ||
*Stroma: | *Stroma: | ||
**Cellular stroma (spindle cells). | **Cellular stroma (spindle cells). | ||
**Mitoses. | **Mitoses. | ||
***Usually harder to find than in the glands. | ***Usually harder to find than in the glands. | ||
Notes: | |||
* † McCluggage says one shouldn't call ''PPE'' without mitoses, as some pseudostratification can be seen in [[atrophic endometrium]].<ref name=pmid16873562>{{Cite journal | last1 = McCluggage | first1 = WG. | title = My approach to the interpretation of endometrial biopsies and curettings. | journal = J Clin Pathol | volume = 59 | issue = 8 | pages = 801-12 | month = Aug | year = 2006 | doi = 10.1136/jcp.2005.029702 | PMID = 16873562 }}</ref> | |||
** There is no guidance on how hard one should look. VL suggests searching ~ 10 mm^2 with the 20x objective. This represents approximately ~ 10 fields of view with a microscope that has a 22 mm eye piece. | |||
* Significant negatives: | |||
** No vacuolation. | |||
** No mucus secretion. | |||
DDx: | DDx: | ||