49,294
edits
Difference between revisions of "Ovarian tumours"
Jump to navigation
Jump to search
→General: re-org
m (→Gross) |
(→General: re-org) |
||
| Line 485: | Line 485: | ||
===General=== | ===General=== | ||
Prognosis: | |||
* Worse prognosis versus other surface epithelial tumours.<ref name=pmid18035678>{{cite journal |author=Hauptmann S, Köbel M |title=[Prognostic factors in ovarian carcinoma] |language=German |journal=Verh Dtsch Ges Pathol |volume=89 |issue= |pages=92-100 |year=2005 |pmid=18035678 |doi= |url=}}</ref> | * Worse prognosis versus other surface epithelial tumours.<ref name=pmid18035678>{{cite journal |author=Hauptmann S, Köbel M |title=[Prognostic factors in ovarian carcinoma] |language=German |journal=Verh Dtsch Ges Pathol |volume=89 |issue= |pages=92-100 |year=2005 |pmid=18035678 |doi= |url=}}</ref> | ||
**Poor response to platinum-based chemotherapy.<ref name=pmid22885379/> | **Poor response to platinum-based chemotherapy.<ref name=pmid22885379/> | ||
**~2.5x risk for thromboembolism compared to other ovarian carcinomas.<ref name=pmid19922988>{{Cite journal | last1 = Duska | first1 = LR. | last2 = Garrett | first2 = L. | last3 = Henretta | first3 = M. | last4 = Ferriss | first4 = JS. | last5 = Lee | first5 = L. | last6 = Horowitz | first6 = N. | title = When 'never-events' occur despite adherence to clinical guidelines: the case of venous thromboembolism in clear cell cancer of the ovary compared with other epithelial histologic subtypes. | journal = Gynecol Oncol | volume = 116 | issue = 3 | pages = 374-7 | month = Mar | year = 2010 | doi = 10.1016/j.ygyno.2009.10.069 | PMID = 19922988 }}</ref> | |||
Epidemiology: | |||
* Asians appear to be at an increased risk.<ref name=pmid22885379>{{Cite journal | last1 = Offman | first1 = SL. | last2 = Longacre | first2 = TA. | title = Clear cell carcinoma of the female genital tract (not everything is as clear as it seems). | journal = Adv Anat Pathol | volume = 19 | issue = 5 | pages = 296-312 | month = Sep | year = 2012 | doi = 10.1097/PAP.0b013e31826663b1 | PMID = 22885379 }}</ref> | * Asians appear to be at an increased risk.<ref name=pmid22885379>{{Cite journal | last1 = Offman | first1 = SL. | last2 = Longacre | first2 = TA. | title = Clear cell carcinoma of the female genital tract (not everything is as clear as it seems). | journal = Adv Anat Pathol | volume = 19 | issue = 5 | pages = 296-312 | month = Sep | year = 2012 | doi = 10.1097/PAP.0b013e31826663b1 | PMID = 22885379 }}</ref> | ||
* Thought to be related to endometrioid carcinoma.<ref name=Ref_PBoD1098>{{Ref PBoD |1098}}</ref> | |||
Association with endometriosis:<ref name=pmid22885379/> | *Association with endometriosis:<ref name=pmid22885379/> | ||
* Increased risk of ovarian clear cell carcinoma ~ 3x. | ** Increased risk of ovarian clear cell carcinoma ~ 3x. | ||
* Seen in 50-70% of ovarian CCC. | ** Seen in 50-70% of ovarian CCC. | ||
===Gross=== | ===Gross=== | ||