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Difference between revisions of "Endometrial carcinoma"
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→Clear cell carcinoma of the endometrium: expand
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===General=== | ===General=== | ||
*Ten-year survival ~ 40%.<ref name=pmid8859187>{{Cite journal | last1 = Abeler | first1 = VM. | last2 = Vergote | first2 = IB. | last3 = Kjørstad | first3 = KE. | last4 = Tropé | first4 = CG. | title = Clear cell carcinoma of the endometrium. Prognosis and metastatic pattern. | journal = Cancer | volume = 78 | issue = 8 | pages = 1740-7 | month = Oct | year = 1996 | doi = | PMID = 8859187 }}</ref> | *Ten-year survival ~ 40%.<ref name=pmid8859187>{{Cite journal | last1 = Abeler | first1 = VM. | last2 = Vergote | first2 = IB. | last3 = Kjørstad | first3 = KE. | last4 = Tropé | first4 = CG. | title = Clear cell carcinoma of the endometrium. Prognosis and metastatic pattern. | journal = Cancer | volume = 78 | issue = 8 | pages = 1740-7 | month = Oct | year = 1996 | doi = | PMID = 8859187 }}</ref> | ||
*Uncommon <=5 % of endometrial carcinomas.<ref name=pmid22885379>{{Cite journal | last1 = Offman | first1 = SL. | last2 = Longacre | first2 = TA. | title = Clear cell carcinoma of the female genital tract (not everything is as clear as it seems). | journal = Adv Anat Pathol | volume = 19 | issue = 5 | pages = 296-312 | month = Sep | year = 2012 | doi = 10.1097/PAP.0b013e31826663b1 | PMID = 22885379 }}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
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DDx: | DDx: | ||
*[[Serous endometrial carcinoma]] - usually has more nuclear pleomorphism, esp. cell size variation. | *[[Serous endometrial carcinoma]] - usually has more nuclear pleomorphism, esp. cell size variation. | ||
*High grade [[endometrioid endometrial carcinoma]]. | *High grade [[endometrioid endometrial carcinoma]] - have non-clear areas.<ref name=pmid22885379/> | ||
*[[Arias-Stella reaction]] - esp. in the context of [[pregnancy]]. | *[[Arias-Stella reaction]] - esp. in the context of [[pregnancy]]. | ||
*Papillary cystadenoma - benign; bland nuclei.<ref name=pmid22885379/> | |||
===IHC=== | ===IHC=== | ||