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===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Plasma cells. | *Plasma cells - '''key feature'''. | ||
**May be sterile, i.e. no organisms. | **May be sterile, i.e. no organisms. | ||
*+/-Fibrosis. | |||
*+/-Necrotic bone - bone with empty lacunae. | |||
*+/-[[Amyloid]]. | *+/-[[Amyloid]]. | ||
**~10% of patients in one series.<ref name=pmid2071276>{{Cite journal | last1 = Alabi | first1 = ZO. | last2 = Ojo | first2 = OS. | last3 = Odesanmi | first3 = WO. | title = Secondary amyloidosis in chronic osteomyelitis. | journal = Int Orthop | volume = 15 | issue = 1 | pages = 21-2 | month = | year = 1991 | doi = | PMID = 2071276 }}</ref> | **~10% of patients in one series.<ref name=pmid2071276>{{Cite journal | last1 = Alabi | first1 = ZO. | last2 = Ojo | first2 = OS. | last3 = Odesanmi | first3 = WO. | title = Secondary amyloidosis in chronic osteomyelitis. | journal = Int Orthop | volume = 15 | issue = 1 | pages = 21-2 | month = | year = 1991 | doi = | PMID = 2071276 }}</ref> | ||
Image: | |||
*[http://osteomyelitis.stanford.edu/pages/histo_001.html Chronic osteomyelitis (stanford.edu)]. | |||
=Bone tumours= | =Bone tumours= |
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