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Difference between revisions of "Testis"
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→Seminoma: +SO
(→IHC) |
(→Seminoma: +SO) |
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*Cytokeratins usu. -ve, may have weak focal positivity.<ref name=pmid16867864/> | *Cytokeratins usu. -ve, may have weak focal positivity.<ref name=pmid16867864/> | ||
*OCT3/4 +ve.<ref name=pmid20438407>{{Cite journal | last1 = Emerson | first1 = RE. | last2 = Ulbright | first2 = TM. | title = Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers. | journal = Pathology | volume = 42 | issue = 4 | pages = 344-55 | month = Jun | year = 2010 | doi = 10.3109/00313021003767355 | PMID = 20438407 }}</ref> | *OCT3/4 +ve.<ref name=pmid20438407>{{Cite journal | last1 = Emerson | first1 = RE. | last2 = Ulbright | first2 = TM. | title = Intratubular germ cell neoplasia of the testis and its associated cancers: the use of novel biomarkers. | journal = Pathology | volume = 42 | issue = 4 | pages = 344-55 | month = Jun | year = 2010 | doi = 10.3109/00313021003767355 | PMID = 20438407 }}</ref> | ||
===Sign out=== | |||
<pre> | |||
RETROPERITONEAL SOFT TISSUE, RIGHT, CORE BIOPSY: | |||
- SEMINOMA. | |||
</pre> | |||
====Micro==== | |||
The sections show large atypical, discohesive cells with prominent nucleoli, central | |||
nuclei and moderate clear cytoplasm, intermixed with mature lymphocytes. Mitotic | |||
activity is present. | |||
====Small biopsy==== | |||
A mixed germ cell tumour cannot be excluded; given the small quantity of tumour, this | |||
biopsy is at a high risk for having undersampled other tumour components should they be | |||
present. Correlation with serology and consideration of re-biopsy is suggested. | |||
==Spermatocytic seminoma== | ==Spermatocytic seminoma== | ||