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Difference between revisions of "Ampulla of Vater"
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*Textbook association: [[familial adenomatous polyposis]].<ref name=pmid15756395>{{Cite journal | last1 = Tran | first1 = TC. | last2 = Vitale | first2 = GC. | title = Ampullary tumors: endoscopic versus operative management. | journal = Surg Innov | volume = 11 | issue = 4 | pages = 255-63 | month = Dec | year = 2004 | doi = | PMID = 15756395 }}</ref><ref name=pmid9834381>{{Cite journal | last1 = Soravia | first1 = C. | last2 = Berk | first2 = T. | last3 = Haber | first3 = G. | last4 = Cohen | first4 = Z. | last5 = Gallinger | first5 = S. | title = Management of advanced duodenal polyposis in familial adenomatous polyposis. | journal = J Gastrointest Surg | volume = 1 | issue = 5 | pages = 474-8 | month = | year = | doi = | PMID = 9834381 }}</ref> | *Textbook association: [[familial adenomatous polyposis]].<ref name=pmid15756395>{{Cite journal | last1 = Tran | first1 = TC. | last2 = Vitale | first2 = GC. | title = Ampullary tumors: endoscopic versus operative management. | journal = Surg Innov | volume = 11 | issue = 4 | pages = 255-63 | month = Dec | year = 2004 | doi = | PMID = 15756395 }}</ref><ref name=pmid9834381>{{Cite journal | last1 = Soravia | first1 = C. | last2 = Berk | first2 = T. | last3 = Haber | first3 = G. | last4 = Cohen | first4 = Z. | last5 = Gallinger | first5 = S. | title = Management of advanced duodenal polyposis in familial adenomatous polyposis. | journal = J Gastrointest Surg | volume = 1 | issue = 5 | pages = 474-8 | month = | year = | doi = | PMID = 9834381 }}</ref> | ||
*Prognosis guarded but significantly better than [[pancreatic ductal adenocarcinoma]] - 5 year survival ~40% for ampullary carcinomas vs. 10% for pancreatic adenocarcinoma.<ref name=pmid23026934/> | *Prognosis guarded but significantly better than [[pancreatic ductal adenocarcinoma]] - 5 year survival ~40% for ampullary carcinomas vs. 10% for pancreatic adenocarcinoma.<ref name=pmid23026934/> | ||
===Gross=== | |||
*Ampullary carcinomas are classified by site. | |||
*Modest differences exist in survival between the sites. | |||
====Classification==== | ====Classification==== | ||
| Line 49: | Line 53: | ||
! Prevalence | ! Prevalence | ||
! Origin/definition | ! Origin/definition | ||
! Notes | ! Notes | ||
|- | |- | ||
| Intra-ampullary papillary-tubular carcinoma | | Intra-ampullary papillary-tubular carcinoma | ||
| Line 63: | Line 67: | ||
| Peri-ampullary duodenal carcinoma | | Peri-ampullary duodenal carcinoma | ||
| ~5% of cases | | ~5% of cases | ||
| primarily in the | | primarily in the duodenum; ampullary orfice must be clearly within lesion | ||
| | | | ||
|- | |- | ||
| Ampullary carcinoma not otherwise specified | | Ampullary carcinoma not otherwise specified | ||
| Line 85: | Line 89: | ||
*Ectopic pancreas.<ref name=pmid18304504>{{Cite journal | last1 = Hsu | first1 = SD. | last2 = Chan | first2 = DC. | last3 = Hsieh | first3 = HF. | last4 = Chen | first4 = TW. | last5 = Yu | first5 = JC. | last6 = Chou | first6 = SJ. | title = Ectopic pancreas presenting as ampulla of Vater tumor. | journal = Am J Surg | volume = 195 | issue = 4 | pages = 498-500 | month = Apr | year = 2008 | doi = 10.1016/j.amjsurg.2007.01.043 | PMID = 18304504 }} | *Ectopic pancreas.<ref name=pmid18304504>{{Cite journal | last1 = Hsu | first1 = SD. | last2 = Chan | first2 = DC. | last3 = Hsieh | first3 = HF. | last4 = Chen | first4 = TW. | last5 = Yu | first5 = JC. | last6 = Chou | first6 = SJ. | title = Ectopic pancreas presenting as ampulla of Vater tumor. | journal = Am J Surg | volume = 195 | issue = 4 | pages = 498-500 | month = Apr | year = 2008 | doi = 10.1016/j.amjsurg.2007.01.043 | PMID = 18304504 }} | ||
</ref> | </ref> | ||
*[[Duodenal adenocarcinoma]] with secondary involvement of the ampulla. | |||
====Intestinal ampullary carcinoma==== | ====Intestinal ampullary carcinoma==== | ||