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Difference between revisions of "Prostate gland"
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→Prostatic adenocarcinoma: +SO section
(→Mimics: +image links) |
(→Prostatic adenocarcinoma: +SO section) |
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*Fusion gene seen in approx. 50% of prostate cancer.<ref name=omim602060>{{OMIM|602060}}</ref> | *Fusion gene seen in approx. 50% of prostate cancer.<ref name=omim602060>{{OMIM|602060}}</ref> | ||
*A subset of ''TMPRSS2-ERG'' known as ''2+Edel'' (seen in ~7% of all prostate cancer cases) predicts poor survival.<ref name=pmid17637754>{{Cite journal | last1 = Attard | first1 = G. | last2 = Clark | first2 = J. | last3 = Ambroisine | first3 = L. | last4 = Fisher | first4 = G. | last5 = Kovacs | first5 = G. | last6 = Flohr | first6 = P. | last7 = Berney | first7 = D. | last8 = Foster | first8 = CS. | last9 = Fletcher | first9 = A. | title = Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. | journal = Oncogene | volume = 27 | issue = 3 | pages = 253-63 | month = Jan | year = 2008 | doi = 10.1038/sj.onc.1210640 | PMID = 17637754 }}</ref> | *A subset of ''TMPRSS2-ERG'' known as ''2+Edel'' (seen in ~7% of all prostate cancer cases) predicts poor survival.<ref name=pmid17637754>{{Cite journal | last1 = Attard | first1 = G. | last2 = Clark | first2 = J. | last3 = Ambroisine | first3 = L. | last4 = Fisher | first4 = G. | last5 = Kovacs | first5 = G. | last6 = Flohr | first6 = P. | last7 = Berney | first7 = D. | last8 = Foster | first8 = CS. | last9 = Fletcher | first9 = A. | title = Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer. | journal = Oncogene | volume = 27 | issue = 3 | pages = 253-63 | month = Jan | year = 2008 | doi = 10.1038/sj.onc.1210640 | PMID = 17637754 }}</ref> | ||
===Sign out=== | |||
====Completely negative==== | |||
<pre> | |||
A. PROSTATE, RIGHT LATERAL SUPERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
B. PROSTATE, RIGHT MEDIAL SUPERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
C. PROSTATE, RIGHT LATERAL MIDZONE, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
D. PROSTATE, RIGHT MEDIAL MIDZONE, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
E. PROSTATE, RIGHT LATERAL INTERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
F. PROSTATE, RIGHT MEDIAL INFERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
G. PROSTATE, LEFT LATERAL SUPERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
H. PROSTATE, LEFT MEDIAL SUPERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
I. PROSTATE, LEFT LATERAL MIDZONE, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
J. PROSTATE, LEFT MEDIAL MIDZONE, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
K. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
L. PROSTATE, LEFT MEDIAL INFERIOR, BIOPSY: | |||
- BENIGN PROSTATE TISSUE. | |||
</pre> | |||
====No glands==== | |||
<pre> | |||
F. PROSTATE, RIGHT MEDIAL MIDZONE, BIOPSY: | |||
- BENIGN FIBROMUSCULAR TISSUE; | |||
- NO PROSTATIC GLANDULAR TISSUE PRESENT. | |||
</pre> | |||
====Positive==== | |||
<pre> | |||
G. PROSTATE, LEFT LATERAL SUPERIOR, BIOPSY: | |||
- ADENOCARCINOMA, GLEASON SCORE 8/10 (4+4); | |||
- 1/1 CORE INVOLVED; APPROXIMATELY 15% OF TISSUE INVOLVED. | |||
</pre> | |||
<pre> | |||
H. PROSTATE, LEFT MEDIAL SUPERIOR, BIOPSY: | |||
- ADENOCARCINOMA, GLEASON SCORE 7/10 (4+3); | |||
- 1/1 CORE INVOLVED; APPROXIMATELY 5% OF TISSUE INVOLVED; | |||
- FOCAL PERINEURAL INVASION PRESENT. | |||
</pre> | |||
=Unusual forms of prostate cancer= | =Unusual forms of prostate cancer= | ||