Difference between revisions of "Gallbladder"

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609 bytes added ,  18:28, 26 September 2012
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*Antral type metaplasia --> intestinal metaplasia --> dysplasia --> carcinoma.
*Antral type metaplasia --> intestinal metaplasia --> dysplasia --> carcinoma.


==Intestinal metaplasia==
==Intestinal metaplasia of the gallbladder==
===General===
===General===
Significance:
Significance:
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===Microscopic===
===Microscopic===
Features:
Features:<ref name=pmid2872152>{{Cite journal  | last1 = Albores-Saavedra | first1 = J. | last2 = Nadji | first2 = M. | last3 = Henson | first3 = DE. | last4 = Ziegels-Weissman | first4 = J. | last5 = Mones | first5 = JM. | title = Intestinal metaplasia of the gallbladder: a morphologic and immunocytochemical study. | journal = Hum Pathol | volume = 17 | issue = 6 | pages = 614-20 | month = Jun | year = 1986 | doi =  | PMID = 2872152 }}</ref>
*Presence of [[goblet cell]]s -/+ Paneth cells.<ref name=Ref_Sternberg4_1789>{{Ref Sternberg4|1789}}</ref>
*[[Goblet cell]]s - '''key feature'''.
*+/-Paneth cells.<ref name=Ref_Sternberg4_1789>{{Ref Sternberg4|1789}}</ref>
 
Note:
*Often accompanied by antral type metplasia.
**Gastric antral-type epithelium - may form glands.
 
DDx:
*[[Gallbladder adenocarcinoma]].


Image:
Image:
48,536

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