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Difference between revisions of "Immunohistochemical staining"
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Immunohistochemical staining (view source)
Revision as of 11:35, 19 September 2012
, 11:35, 19 September 2012→Proliferation markers: more
(→Sarcomas cytokeratins: +see also) |
(→Proliferation markers: more) |
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*MIB1 - an antibody against the protein ''Ki-67'' (a protein expressed in proliferating cells). | *MIB1 - an antibody against the protein ''Ki-67'' (a protein expressed in proliferating cells). | ||
Notes: | |||
*Ki-67 is found in lymphocytes - these are a positive control; lymphocytes should ''not'' be confused for (positive) tumour cells.<ref name=pmid22517707>{{Cite journal | last1 = Hadzi-Mihailovic | first1 = M. | last2 = Cakic | first2 = S. | last3 = Jankovic | first3 = S. | last4 = Raybaud | first4 = H. | last5 = Nedeljkovic | first5 = N. | last6 = Jankovic | first6 = L. | title = Ki-67 expression in oral lichen planus. | journal = J BUON | volume = 17 | issue = 1 | pages = 132-7 | month = | year = | doi = | PMID = 22517707 }}</ref> | |||
*''MIB1'' should not be confused with ''mindbomb homolog 1'' (''MIB-1''), a gene that regulates [[apoptosis]].<ref>[http://www.genenames.org/data/hgnc_data.php?hgnc_id=21086 http://www.genenames.org/data/hgnc_data.php?hgnc_id=21086]</ref> | |||
==Carcinomas== | ==Carcinomas== | ||