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Difference between revisions of "Colorectal tumours"
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→Intratumoural lymphocytic response: different definitions
(→Intratumoural lymphocytic response: +URL in ref) |
(→Intratumoural lymphocytic response: different definitions) |
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*Finding is suggestive of microsatellite instabillity. | *Finding is suggestive of microsatellite instabillity. | ||
**May be seen in the context of [[Lynch syndrome]]. | **May be seen in the context of [[Lynch syndrome]]. | ||
=====Microscopic===== | =====Microscopic===== | ||
Features: | Features: | ||
*Lymphocytes between tumour cell tumours.<ref name=pmid19638537/> | *Lymphocytes between tumour cell tumours. † <ref name=pmid19638537/> | ||
**Other lymphocytes do not count. | **Other lymphocytes do not count. | ||
Note: | |||
* † Definitions vary substantially - some authors consider lymphocytes adjacent to the tumour (in the stroma around the tumour cells) "intratumoural".<reF name=pmid9349235>{{Cite journal | last1 = Ropponen | first1 = KM. | last2 = Eskelinen | first2 = MJ. | last3 = Lipponen | first3 = PK. | last4 = Alhava | first4 = E. | last5 = Kosma | first5 = VM. | title = Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer. | journal = J Pathol | volume = 182 | issue = 3 | pages = 318-24 | month = Jul | year = 1997 | doi = 10.1002/(SICI)1096-9896(199707)182:3318::AID-PATH8623.0.CO;2-6 | PMID = 9349235 |URL = http://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291096-9896%28199707%29182:3%3C318::AID-PATH862%3E3.0.CO;2-6/pdf}}</ref> | |||
Images: | Images: | ||