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Difference between revisions of "Inflammatory bowel disease"
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Inflammatory bowel disease (view source)
Revision as of 01:50, 11 September 2012
, 01:50, 11 September 2012→Crohn's disease: +SO, expand general
(→Crohn's disease: +SO, expand general) |
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==Crohn's disease== | ==Crohn's disease== | ||
*Often abbreviated as ''CD''. | |||
===General=== | ===General=== | ||
* | *Autoimmune disease. | ||
*Increased risk for cancer - usu. rectal cancer; classically mucinous adenocarcinoma. | *Increased risk for cancer - usu. rectal cancer; classically [[colorectal adenocarcinoma|mucinous adenocarcinoma]]. | ||
Associations:<ref name=pmid20074146>{{Cite journal | last1 = Gearry | first1 = RB. | last2 = Richardson | first2 = AK. | last3 = Frampton | first3 = CM. | last4 = Dodgshun | first4 = AJ. | last5 = Barclay | first5 = ML. | title = Population-based cases control study of inflammatory bowel disease risk factors. | journal = J Gastroenterol Hepatol | volume = 25 | issue = 2 | pages = 325-33 | month = Feb | year = 2010 | doi = 10.1111/j.1440-1746.2009.06140.x | PMID = 20074146 }} | |||
</ref> | |||
*High socioeconomic status. | |||
*Family history of [[IBD]]. | |||
*City dwellers. | |||
*Not breastfed. | |||
Treatment: | |||
*Immune suppression. | |||
*Surgery considered treatment of last resort. | |||
===Gross=== | ===Gross=== | ||
| Line 217: | Line 229: | ||
**[[Amebiasis]]. | **[[Amebiasis]]. | ||
*[[Ulcerative colitis]]. | *[[Ulcerative colitis]]. | ||
===Sign-out=== | |||
<pre> | |||
A. TERMINAL ILEUM, BIOPSY | |||
- MODERATE GRANULOMATOUS ILEITIS. | |||
B. CECUM, BIOPSY: | |||
- MILD PATCHY ACTIVE COLITIS. | |||
C. SIGMOID COLON, BIOPSY: | |||
- CHRONIC INFLAMMATORY CHANGES. NO ACTIVE COLITIS. | |||
COMMENT: | |||
The histomorphological findings (patchy inflammation, granulomas, ileitis, paneth cell | |||
metaplasia, crypt loss and crypt elongation) are suggestive of Crohn's disease. An infective | |||
etiology should be considered, as it cannot be definitely excluded on pathologic grounds. | |||
</pre> | |||
=="Indeterminate colitis"== | =="Indeterminate colitis"== | ||