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Difference between revisions of "Fibroblastic/myofibroblastic tumours"
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Fibroblastic/myofibroblastic tumours (view source)
Revision as of 19:39, 10 September 2012
, 19:39, 10 September 2012subdivide into non-malignant and malignant section, move 'calcifying fibrous tumour' up
m (→List of tumours: w) |
(subdivide into non-malignant and malignant section, move 'calcifying fibrous tumour' up) |
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This article covers '''fibroblastic/myofibroblastic tumours'''. These tumours fit into the larger category of [[soft tissue lesions]]. | This article covers '''fibroblastic/myofibroblastic tumours'''. These tumours fit into the larger category of [[soft tissue lesions]]. | ||
=List of tumours= | |||
===Benign=== | ===Benign=== | ||
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*[[Low-grade fibromyxoid sarcoma]] (hyalinizing spindle cell tumour). | *[[Low-grade fibromyxoid sarcoma]] (hyalinizing spindle cell tumour). | ||
*Sclerosing epithelioid fibrosarcoma. | *Sclerosing epithelioid fibrosarcoma. | ||
=Non-malignant= | |||
==Inflammatory myofibroblastic tumour== | ==Inflammatory myofibroblastic tumour== | ||
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**+ve in [[desmoid-type fibromatosis]]. | **+ve in [[desmoid-type fibromatosis]]. | ||
==Calcifying fibrous tumour== | |||
===General=== | |||
*Rare. | |||
*Benign. | |||
===Microscopic=== | |||
Features:<ref name=pmid16858502>{{cite journal |author=Attila T, Chen D, Gardiner GW, Ptak TW, Marcon NE |title=Gastric calcifying fibrous tumor |journal=Can. J. Gastroenterol. |volume=20 |issue=7 |pages=487–9 |year=2006 |month=July |pmid=16858502 |pmc=2659917 |doi= |url=http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659917/}}</ref> | |||
*Submucosal circumscribed fibrocollagenous nodule. | |||
*Psammomatous calcifications. | |||
*Focal plasma cells at the periphery. | |||
=Malignant= | |||
==Low-grade fibromyxoid sarcoma== | ==Low-grade fibromyxoid sarcoma== | ||
*[[AKA]] ''hyalinizing spindle cell tumour''. | *[[AKA]] ''hyalinizing spindle cell tumour''. | ||
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*t(7;16)(q33;p11).<ref>{{cite journal |author=Panagopoulos I, Storlazzi CT, Fletcher CD, ''et al.'' |title=The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma |journal=Genes Chromosomes Cancer |volume=40 |issue=3 |pages=218–28 |year=2004 |month=July |pmid=15139001 |doi=10.1002/gcc.20037 |url=}}</ref> | *t(7;16)(q33;p11).<ref>{{cite journal |author=Panagopoulos I, Storlazzi CT, Fletcher CD, ''et al.'' |title=The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma |journal=Genes Chromosomes Cancer |volume=40 |issue=3 |pages=218–28 |year=2004 |month=July |pmid=15139001 |doi=10.1002/gcc.20037 |url=}}</ref> | ||
*t(11;16).<ref name=Ref_WMSP611>{{Ref WMSP|611}}</ref> | *t(11;16).<ref name=Ref_WMSP611>{{Ref WMSP|611}}</ref> | ||
==Adult fibrosarcoma== | ==Adult fibrosarcoma== | ||
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*Vimentin +ve -- otherwise non-distinctive.<ref name=Ref_WMSP612-3>{{Ref WMSP|612-3}}</ref> | *Vimentin +ve -- otherwise non-distinctive.<ref name=Ref_WMSP612-3>{{Ref WMSP|612-3}}</ref> | ||
=See also= | |||
*[[Soft tissue lesions]]. | *[[Soft tissue lesions]]. | ||
=References= | |||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Soft tissue lesions]] | [[Category:Soft tissue lesions]] | ||