Difference between revisions of "Non-malignant skin disease"

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*Clusters of cells with brown granular material in the superficial dermis/dermoepidermal junction - pigmented melanocytes.  
*Clusters of cells with brown granular material in the superficial dermis/dermoepidermal junction - pigmented melanocytes.  


DDx:<ref>{{Ref Derm|338-9}}</ref>
DDx:<ref name=Ref_Derm338-9>{{Ref Derm|338-9}}</ref>
*[[Actinic keratosis]] - irritated SK
*[[Actinic keratosis]] - irritated SK
*[[Verruca vulgaris]] - SK may have papillomatous projections.
*[[Verruca vulgaris]] - SK may have papillomatous projections.
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*[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1985374774 Seborrheic keratosis - high mag. (dermatlas.org)].
*[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1985374774 Seborrheic keratosis - high mag. (dermatlas.org)].
*[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1880960893 Seborrheic keratosis - low mag.  (dermatlas.org)].
*[http://www.dermatlas.org/derm/IndexDisplay.cfm?ImageID=-1880960893 Seborrheic keratosis - low mag.  (dermatlas.org)].
====Histologic subtypes====
Like very common lesion, there are subtypes:<ref name=Ref_Derm338-9>{{Ref Derm|338-9}}</ref>
*Acanthotic seborrheic keratosis - thickened ''stratum spinosum''; thick epidermis.
*Reticulated seborrheic keratosis - vaguely resembles [[fibroepithelioma of Pinkus]] (BCC, fibroepitheliomatous pattern).
*Irritated seborrheice keratosis - spongiosis (epidermal intercellular edema) and inflammation.
*Digitated seborrheic keratosis - papillomatous projections.


==Pilomatricoma==
==Pilomatricoma==
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