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Difference between revisions of "Stomach"
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→Pernicious anemia: more, tweak
(→Reactive gastropathy: +DDx) |
(→Pernicious anemia: more, tweak) |
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| Line 444: | Line 444: | ||
*Etiology: autoimmune. | *Etiology: autoimmune. | ||
Diagnosis based serology for antibodies to:<ref name=pmid12643357>{{Cite journal | last1 = Oh | first1 = R. | last2 = Brown | first2 = DL. | title = Vitamin B12 deficiency. | journal = Am Fam Physician | volume = 67 | issue = 5 | pages = 979-86 | month = Mar | year = 2003 | doi = | PMID = 12643357 }}</ref> | Diagnosis based on serology for antibodies to:<ref name=pmid12643357>{{Cite journal | last1 = Oh | first1 = R. | last2 = Brown | first2 = DL. | title = Vitamin B12 deficiency. | journal = Am Fam Physician | volume = 67 | issue = 5 | pages = 979-86 | month = Mar | year = 2003 | doi = | PMID = 12643357 }}</ref> | ||
*Parietal cells. | *Parietal cells. | ||
*Intrinsic factor. | *Intrinsic factor. | ||
| Line 457: | Line 457: | ||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*Corpus predominant inflammation. | *Corpus predominant inflammation - usu. moderate or severe - '''key feature''' | ||
*Loss of parietal cells. | |||
*Increased G cells in the antrum. | *Increased G cells in the antrum. | ||
** | **Produce gastrin to stimulate the (missing) parietal cells. | ||
DDx: | DDx: | ||