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Difference between revisions of "Non-malignant skin disease"
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Non-malignant skin disease (view source)
Revision as of 12:23, 23 August 2012
, 12:23, 23 August 2012→Lichen simplex chronicus: +PN separate
(→Lichen simplex chronicus: +PN separate) |
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*Pruritus (itchness) -> mechanical trauma -> lichenification (thickened/leathery<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=10131 http://www.medterms.com/script/main/art.asp?articlekey=10131]. Accessed on: 20 August 2010.</ref>. | *Pruritus (itchness) -> mechanical trauma -> lichenification (thickened/leathery<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=10131 http://www.medterms.com/script/main/art.asp?articlekey=10131]. Accessed on: 20 August 2010.</ref>. | ||
===Microscopic=== | ===Microscopic=== | ||
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*Spongiosis (epidermal intercellular edema -- cells appear to have a clear halo around 'em). | *Spongiosis (epidermal intercellular edema -- cells appear to have a clear halo around 'em). | ||
*Parakeratosis = retention of nuclei in the stratum corneum. | *Parakeratosis = retention of nuclei in the stratum corneum. | ||
DDx: | |||
*[[Prurigo nodularis]] - focal process (nodule or papule). | |||
Images: | Images: | ||
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- Negative for malignancy. | - Negative for malignancy. | ||
</pre> | </pre> | ||
==Prurigo nodularis== | |||
*Abbreviated ''PN''. | |||
*[[AKA]] ''chronic prurigo'' and ''picker nodule''.<ref name=Ref_Derm26>{{Ref Derm|26}}</ref> | |||
===General=== | |||
*Can be thought of as a localized/focal version of [[lichen simplex chronicus]] (LSC). | |||
===Gross=== | |||
*Dome-shaped/raised - papular (<1 cm) ''or'' nodular (>1 cm).<ref>URL: [http://www.pediatrics.wisc.edu/education/derm/text.html http://www.pediatrics.wisc.edu/education/derm/text.html]. Accessed on: 23 August 2012.</ref> | |||
===Microscopic=== | |||
*See ''[[lichen simplex chronicus]]''. | |||
DDx: | |||
*[[Lichen simplex chronicus]] - more diffuse process. | |||
=Very common= | =Very common= | ||