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Mucinous carcinoma can arise in a number of sites. | Mucinous carcinoma can arise in a number of sites. | ||
==General== | |||
*Often have a better prognosis that tumours without mucinous differentiation. | |||
==Microscopic== | |||
Features: | |||
#Mucin - amphormous whispy or cream material. | |||
#Cytologically atypical cells within the mucin. | |||
#+/-Tumour without mucin. | |||
#*Maximum amount acceptable depends on the primary site (see ''proportion of mucin'' section below). | |||
Note: | |||
*Mucin alone -- should prompt a search for atypical cells, i.e. [[levels]] should be done. | |||
DDx: | |||
*Benign [[mucocele]]. | |||
*[[Adenocarcinoma]] with mucinous features. | |||
===Proportion of mucin=== | |||
The criteria for diagnosing "mucinous carcinoma" varies by the anatomical site: | The criteria for diagnosing "mucinous carcinoma" varies by the anatomical site: | ||
*[[Mucinous prostate carcinoma]]: > 25% of the tumour.<ref name=pmid14976541>{{cite journal |author=Grignon DJ |title=Unusual subtypes of prostate cancer |journal=Mod. Pathol. |volume=17 |issue=3 |pages=316–27 |year=2004 |month=March |pmid=14976541 |doi=10.1038/modpathol.3800052 |url=}}</ref> | *[[Mucinous prostate carcinoma]]: > 25% of the tumour.<ref name=pmid14976541>{{cite journal |author=Grignon DJ |title=Unusual subtypes of prostate cancer |journal=Mod. Pathol. |volume=17 |issue=3 |pages=316–27 |year=2004 |month=March |pmid=14976541 |doi=10.1038/modpathol.3800052 |url=}}</ref> |
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