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*[[Gallbladder adenocarcinoma]]. | *[[Gallbladder adenocarcinoma]]. | ||
*[[Acute cholecystitis]]. | *[[Acute cholecystitis]]. | ||
==Acute cholecystitis== | ==Acute cholecystitis== | ||
===General=== | ===General=== | ||
*Less common than ''chronic cholecystitis''. | *Less common than ''chronic cholecystitis''. | ||
*Usually due to gallstones.<ref name=Ref_Sternberg5_1606>{{Sternberg5|1606}}</ref> | *Usually due to gallstones.<ref name=Ref_Sternberg5_1606>{{Ref Sternberg5|1606}}</ref> | ||
*Classically older individuals (50s and 60s) with a slight female predominance.<ref name=Ref_Sternberg5_1606>{{Sternberg5|1606}}</ref> | *Classically older individuals (50s and 60s) with a slight female predominance.<ref name=Ref_Sternberg5_1606>{{Sternberg5|1606}}</ref> | ||
===Gross=== | ===Gross=== | ||
Features:<ref name=Ref_Sternberg5_1606>{{Sternberg5|1606}}</ref> | Features:<ref name=Ref_Sternberg5_1606>{{Ref Sternberg5|1606}}</ref> | ||
*Wall thickening - due to edema and hemorrhage. | *Wall thickening - due to edema and hemorrhage. | ||
*Gallstone(s) - classically obstructing the gallbladder neck. | *Gallstone(s) - classically obstructing the gallbladder neck. | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=Ref_Sternberg5_1606>{{Sternberg5|1606}}</ref> | Features:<ref name=Ref_Sternberg5_1606>{{Ref Sternberg5|1606}}</ref> | ||
*Edema. | *Edema. | ||
*Hemorrhage. | *Hemorrhage. | ||
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**Not essential for the Dx of ''acute cholecystitis''. | **Not essential for the Dx of ''acute cholecystitis''. | ||
**Neutrophils usually secondary to [[necrosis]]/ulceration or infection.<ref name=Ref_DCHH174>{{Ref DCHH|174}}</ref> | **Neutrophils usually secondary to [[necrosis]]/ulceration or infection.<ref name=Ref_DCHH174>{{Ref DCHH|174}}</ref> | ||
====Special types==== | |||
=====Gangrenous cholecystitis===== | |||
General:<ref name=pmid21762298>{{Cite journal | last1 = Nikfarjam | first1 = M. | last2 = Niumsawatt | first2 = V. | last3 = Sethu | first3 = A. | last4 = Fink | first4 = MA. | last5 = Muralidharan | first5 = V. | last6 = Starkey | first6 = G. | last7 = Jones | first7 = RM. | last8 = Christophi | first8 = C. | title = Outcomes of contemporary management of gangrenous and non-gangrenous acute cholecystitis. | journal = HPB (Oxford) | volume = 13 | issue = 8 | pages = 551-8 | month = Aug | year = 2011 | doi = 10.1111/j.1477-2574.2011.00327.x | PMID = 21762298 }}</ref> | |||
*Older. | |||
*Clinically "sicker". | |||
*Worse outcome than (acute) non-gangrenous cholecystitis. | |||
Microscopic: | |||
*[[Necrosis]] of gallbladder wall (muscularis propria).<ref>STC. 25 February 2009.</ref> | |||
==Gallbladder cholesterolosis== | ==Gallbladder cholesterolosis== |
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