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(→Classification of amyloid - differentiation: tweak, IHC disputed) |
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===Immunohistochemistry=== | ===Immunohistochemistry=== | ||
*[[IHC]] may be useful for subclassification of | *[[IHC]] may be useful for the subclassification of amyloidoses.<ref name=pmid19756621>{{cite journal |author=Röcken C |title=[Update on immunohistological classification of amyloidoses] |language=German |journal=Pathologe |volume=30 Suppl 2 |issue= |pages=121–3 |year=2009 |month=December |pmid=19756621 |doi=10.1007/s00292-009-1183-7 |url=}}</ref> | ||
**The | **The reliability of IHC for the subclassification of amyloidoses is thought to be low.<ref name=pmid18181665>{{Cite journal | last1 = Solomon | first1 = A. | last2 = Murphy | first2 = CL. | last3 = Westermark | first3 = P. | title = Unreliability of immunohistochemistry for typing amyloid deposits. | journal = Arch Pathol Lab Med | volume = 132 | issue = 1 | pages = 14; author reply 14-5 | month = Jan | year = 2008 | doi = 10.1043/1543-2165(2008)132[14b:IR]2.0.CO;2 | PMID = 18181665 | url = http://www.archivesofpathology.org/doi/pdf/10.1043/1543-2165%282008%29132%5B14b%3AIR%5D2.0.CO%3B2 }}</ref> | ||
Possibly useful immunostains: | |||
*Transthyretin | *Kappa. | ||
*Lambda. | |||
*Transthyretin. | |||
**The name ''transthyretin'' is from '''''trans'''ports '''thy'''roxine and '''retin'''ol'' (previous unknown as ''prealbumin''). | **The name ''transthyretin'' is from '''''trans'''ports '''thy'''roxine and '''retin'''ol'' (previous unknown as ''prealbumin''). | ||
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