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===Stains=== | ===Stains=== | ||
*PAS-D +ve. | *PAS-D +ve. | ||
==Microsporidiosis== | |||
===General=== | |||
*A group of (extremely) small intracellular microorganisms - classified as fungi.<ref name=pmid15777637/> | |||
**Human pathogenic organisms in this group include: ''Enterocytozoon bieneusi'', ''Encephalitozoon hellem'', and ''Encephalitozoon intestinalis''.<ref name=pmid21844802/> | |||
*Important in the context of [[HIV]]/AIDS,<ref name=pmid12775504>{{Cite journal | last1 = Orenstein | first1 = JM. | title = Diagnostic pathology of microsporidiosis. | journal = Ultrastruct Pathol | volume = 27 | issue = 3 | pages = 141-9 | month = | year = | doi = | PMID = 12775504 }}</ref> and solid organ transplant recipients. | |||
*May be seen in immune competent individuals.<ref name=pmid21844802>{{Cite journal | last1 = Didier | first1 = ES. | last2 = Weiss | first2 = LM. | title = Microsporidiosis: not just in AIDS patients. | journal = Curr Opin Infect Dis | volume = 24 | issue = 5 | pages = 490-5 | month = Oct | year = 2011 | doi = 10.1097/QCO.0b013e32834aa152 | PMID = 21844802 }}</ref> | |||
Clinical:<ref name=pmid21844802/> | |||
*Diarrhea. | |||
*Weight loss. | |||
*Abdominal pain. | |||
===Microscopic=== | |||
Features: | |||
*Non-specific changes on light microscopy. | |||
**Partial villus atrophy (villous blunting) and crypt hyperplasia.<ref name=pmid21844802/> | |||
Image: | |||
*[http://images.wellcome.ac.uk/indexplus/result.html?_IXMAXHITS_=1&_IXACTION_=query&_IXFIRST_=5&_IXemailreal=true&_IXbox=50007&_IXSPFX_=templates%2Ft&_IXFPFX_=templates%2Ft Microsporidiosis (wellcome.ac.uk)]. | |||
===EM=== | |||
*Small intracellular microorganisms ~ 1.0-4.0 μm.<ref name=pmid15777637>{{Cite journal | last1 = Didier | first1 = ES. | title = Microsporidiosis: an emerging and opportunistic infection in humans and animals. | journal = Acta Trop | volume = 94 | issue = 1 | pages = 61-76 | month = Apr | year = 2005 | doi = 10.1016/j.actatropica.2005.01.010 | PMID = 15777637 }}</ref> | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Fibrillanosema_spore.jpg Microsporidium (WC)].{{fact}} | |||
=See also= | =See also= |
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