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Difference between revisions of "Peripheral nerve sheath tumours"
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Peripheral nerve sheath tumours (view source)
Revision as of 15:26, 1 June 2012
, 15:26, 1 June 2012→Malignant peripheral nerve sheath tumour: +Triton tumour
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(→Malignant peripheral nerve sheath tumour: +Triton tumour) |
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*p27. | *p27. | ||
*MIB1. | *MIB1. | ||
==Malignant triton tumour== | |||
*Abbreviated ''MTT''. | |||
*[[AKA]] ''malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation''.<ref name=pmid17149968>{{Cite journal | last1 = Stasik | first1 = CJ. | last2 = Tawfik | first2 = O. | title = Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor). | journal = Arch Pathol Lab Med | volume = 130 | issue = 12 | pages = 1878-81 | month = Dec | year = 2006 | doi = 10.1043/1543-2165(2006)130[1878:MPNSTW]2.0.CO;2 | PMID = 17149968 }}</ref> | |||
===General=== | |||
*Rare. | |||
*Considered to be a variant of ''[[MPNST]]''. | |||
*Prognosis worse that conventional MPNST.<ref name=pmid17149968/> | |||
*Diagnosis may require clinical information, i.e. individual has a history of [[neurofibromatosis type 1]]. | |||
Note: | |||
*A handful of ''benign triton tumours'' are reported; these are considered ''neuromuscular [[hamartoma]]s''.<ref name=pmid15814954>{{Cite journal | last1 = Castro | first1 = DE. | last2 = Raghuram | first2 = K. | last3 = Phillips | first3 = CD. | title = Benign triton tumor of the trigeminal nerve. | journal = AJNR Am J Neuroradiol | volume = 26 | issue = 4 | pages = 967-9 | month = Apr | year = 2005 | doi = | PMID = 15814954 }} | |||
</ref> | |||
===Microscopic=== | |||
Features - Woodruff criteria - all required:<ref name=pmid17149968/> | |||
# (a) Tumour arise from a peripheral nerve ''or'' (b) individual has [[NF1]] ''or'' (c) lesion a metastasis arising in the context of (a) or (b). | |||
# Schwann cell tumour characteristics. | |||
# Rhabdomyoblasts. | |||
DDx: | |||
*[[Malignant peripheral nerve sheath tumour]]. | |||
==Morton neuroma== | ==Morton neuroma== | ||