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*Associated with [[systemic lupus erythematosus]]. | *Associated with [[systemic lupus erythematosus]]. | ||
**Seen in approximately in 1/10 SLE cases by echocardiography.<ref name=pmid19946116/> | **Seen in approximately in 1/10 SLE cases by echocardiography.<ref name=pmid19946116/> | ||
*Affects the mitral and aortic valves.<ref name=pmid19089657>{{Cite journal | last1 = Lee | first1 = JL. | last2 = Naguwa | first2 = SM. | last3 = Cheema | first3 = GS. | last4 = Gershwin | first4 = ME. | title = Revisiting Libman-Sacks endocarditis: a historical review and update. | journal = Clin Rev Allergy Immunol | volume = 36 | issue = 2-3 | pages = 126-30 | month = Jun | year = 2009 | doi = 10.1007/s12016-008-8113-y | PMID = 19089657 }}</ref> | *Affects the mitral and aortic valves.<ref name=pmid19089657>{{Cite journal | last1 = Lee | first1 = JL. | last2 = Naguwa | first2 = SM. | last3 = Cheema | first3 = GS. | last4 = Gershwin | first4 = ME. | title = Revisiting Libman-Sacks endocarditis: a historical review and update. | journal = Clin Rev Allergy Immunol | volume = 36 | issue = 2-3 | pages = 126-30 | month = Jun | year = 2009 | doi = 10.1007/s12016-008-8113-y | PMID = 19089657 }}</ref> | ||
**Mitral valve most commonly affected.<ref name=pmid8608627>{{Cite journal | last1 = Hojnik | first1 = M. | last2 = George | first2 = J. | last3 = Ziporen | first3 = L. | last4 = Shoenfeld | first4 = Y. | title = Heart valve involvement (Libman-Sacks endocarditis) in the antiphospholipid syndrome. | journal = Circulation | volume = 93 | issue = 8 | pages = 1579-87 | month = Apr | year = 1996 | doi = | PMID = 8608627 }}</ref> | |||
*It has been suggested that it may be a manifestation of APLA syndrome.<ref name=pmid19089657/><ref name=pmid8608627/> | |||
Clinical: | |||
*Usually regurgitation. | |||
===Gross=== | ===Gross=== | ||
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===Microscopic=== | ===Microscopic=== | ||
Features: | Features:{{fact}} | ||
* | *Fibrin. | ||
*No microorganisms. | |||
*No inflammation. | |||
==Biscupid aortic valve== | ==Biscupid aortic valve== |
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