Difference between revisions of "Neurohistology"

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Neurohistology (view source)

Revision as of 13:23, 31 May 2012

526 bytes added ,  13:23, 31 May 2012
→‎Overview: subdivide, add ganglion
(→‎Overview: subdivide, add ganglion)
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==Overview==
==Overview==
*Neuron:
===Central nervous system===
**Abundant cytoplasm - '''key feature'''.
====Neuron====
**Often very large cells, with angled edges.
*Abundant cytoplasm - '''key feature'''.
**Prominent nucleolus.
*Often very large cells, with angled edges.
**Nissl substance (granular perinuclear material - rough ER).
*Prominent nucleolus.
*Glial cells.
*Nissl substance (granular perinuclear material = rough endoplasmic reticulum).
**Oligodendrocyte.
 
***Small round nuclei (lymphocyte-like nucleus) - '''key feature'''.
====Glial cells====
***May resemble a ''fried egg'' on H&E (clear cytoplasm, central nucleus).
*Oligodendrocyte.
**Astrocyte.
**Small round nuclei (lymphocyte-like nucleus) - '''key feature'''.
***Irregular non-ovoid nucleus - '''key feature'''.
**May resemble a ''fried egg'' on H&E (clear cytoplasm, central nucleus).
***Nuclei less dense than in oligodendrocyte.
*Astrocyte.
***Close to blood vessels.
**Irregular non-ovoid nucleus - '''key feature'''.
***Form blood-brain barrier.
**Nuclei less dense than in oligodendrocyte.
***Cytoplasm normally ''not'' visible.
**Close to blood vessels.
***Image: [http://embryology.med.unsw.edu.au/histology/endocrine/pin42he.jpg astrocyte (med.unsw.edu.au)] (in [http://embryology.med.unsw.edu.au/notes/endocrine12.htm endocrine development]).
**Form blood-brain barrier.
**Microglia - macrophage of the brain (derived from monocyte).
**Cytoplasm normally ''not'' visible.
***May be large.
**Image: [http://embryology.med.unsw.edu.au/histology/endocrine/pin42he.jpg astrocyte (med.unsw.edu.au)] (in [http://embryology.med.unsw.edu.au/notes/endocrine12.htm endocrine development]).
***May have vesicles.
*Microglia - macrophage of the brain (derived from monocyte).
***Rarely seen in normal tissue.
**Typically large cells with abundant cytoplasm.
***Often have vesicles.
**Rarely seen in normal tissue.
*Ependyma.
*Ependyma.
**Simple ciliated cuboidal epithelium.
**Simple ciliated cuboidal epithelium.
**Image: [http://www.stonybrookmedicalcenter.org/sbumcfiles/images/221-001.jpg Ependyma (stonybrookmedicalcenter.org)].
**Image: [http://www.stonybrookmedicalcenter.org/sbumcfiles/images/221-001.jpg Ependyma (stonybrookmedicalcenter.org)].
===Peripheral nervous system===
====Ganglion cell====
*Nerve cell body.
*Found in ganglions - encapsulated body ~ 100-300 μm.
*Large round nucleus with prominent nucleolus - '''key feature'''.
*Abundant eosinophilic granular cytoplasm.
Image:
*[http://commons.wikimedia.org/wiki/File:Ganglion_intermed_mag.jpg Ganglion - intermed. mag. (WC)].
*[http://commons.wikimedia.org/wiki/File:Ganglion_very_high_mag.jpg Ganglion - very high mag. (WC)].


==Normal cellular constituents in a table==
==Normal cellular constituents in a table==
Michael
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