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Difference between revisions of "Neuropathology"
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→Multiple sclerosis: re-arr
(→Multiple sclerosis: re-arr) |
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| Line 578: | Line 578: | ||
Clinical: | Clinical: | ||
*CSF: oligoclonal bands of immunoglobulin.<ref>{{Ref PBoD8|1311}}</ref> | *CSF: oligoclonal bands of immunoglobulin.<ref>{{Ref PBoD8|1311}}</ref> | ||
Classification of MS lesions: | |||
*Early active. | |||
*Inactive. | |||
*Early remyelinating. | |||
*Late remyelinating. | |||
===Radiologic/Gross=== | ===Radiologic/Gross=== | ||
| Line 588: | Line 594: | ||
Features:<ref>URL: [http://library.med.utah.edu/kw/ms/path.html http://library.med.utah.edu/kw/ms/path.html]. Accessed on: 12 July 2010.</ref> | Features:<ref>URL: [http://library.med.utah.edu/kw/ms/path.html http://library.med.utah.edu/kw/ms/path.html]. Accessed on: 12 July 2010.</ref> | ||
*Perivascular inflammation. | *Perivascular inflammation. | ||
**Esp. lymphocytes. | |||
*Demyelination. | *Demyelination. | ||
**Subcortical myelinated fibers are often spared. | **Subcortical myelinated fibers are often spared. | ||
Chronic lesions - specific features:<ref>{{Ref APBR|425 Q43}}</ref> | |||
#Macrophages. | |||
#Astrocyte enlargement. | |||
DDx: | DDx: | ||