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Difference between revisions of "Lymphovascular invasion"
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***Intrahepatic bile duct carcinoma. | ***Intrahepatic bile duct carcinoma. | ||
***[[Hepatocellular carcinoma]].<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Hepatocellular_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Hepatocellular_11protocol.pdf]. Accessed on: 6 April 2012.</ref> | ***[[Hepatocellular carcinoma]].<ref>URL: [http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Hepatocellular_11protocol.pdf http://www.cap.org/apps/docs/committees/cancer/cancer_protocols/2011/Hepatocellular_11protocol.pdf]. Accessed on: 6 April 2012.</ref> | ||
*Absence of LVI in the context of proven [[lymph node metastasis]] = sampling error.<ref name=pmid21545433>{{Cite journal | last1 = Han | first1 = JS. | last2 = Molberg | first2 = KH. | last3 = Sarode | first3 = V. | title = Predictors of invasion and axillary lymph node metastasis in patients with a core biopsy diagnosis of ductal carcinoma in situ: an analysis of 255 cases. | journal = Breast J | volume = 17 | issue = 3 | pages = 223-9 | month = | year = | doi = 10.1111/j.1524-4741.2011.01069.x | PMID = 21545433 }}</ref> | |||
*The prognostic significance of LVI, generally, is dependent on the tumour type and may depend on the tumour stage and lymph node status. | *The prognostic significance of LVI, generally, is dependent on the tumour type and may depend on the tumour stage and lymph node status. | ||
**Most generally -- LVI = poorer prognosis.<ref name=pmid10101593>{{Cite journal | last1 = Moreira | first1 = LF. | last2 = Kenmotsu | first2 = M. | last3 = Gochi | first3 = A. | last4 = Tanaka | first4 = N. | last5 = Orita | first5 = K. | title = Lymphovascular and neural invasion in low-lying rectal carcinoma. | journal = Cancer Detect Prev | volume = 23 | issue = 2 | pages = 123-8 | month = | year = 1999 | doi = | PMID = 10101593 }}</ref> | **Most generally -- LVI = poorer prognosis.<ref name=pmid10101593>{{Cite journal | last1 = Moreira | first1 = LF. | last2 = Kenmotsu | first2 = M. | last3 = Gochi | first3 = A. | last4 = Tanaka | first4 = N. | last5 = Orita | first5 = K. | title = Lymphovascular and neural invasion in low-lying rectal carcinoma. | journal = Cancer Detect Prev | volume = 23 | issue = 2 | pages = 123-8 | month = | year = 1999 | doi = | PMID = 10101593 }}</ref> | ||
===Tumours and LVI=== | |||
* | *[[Urothelial carcinoma]]: LVI is an independent predictor of a poor prognosis that has more predictive power than [[tumour stage]].<ref name=pmid19494855>{{Cite journal | last1 = Cheng | first1 = L. | last2 = Montironi | first2 = R. | last3 = Davidson | first3 = DD. | last4 = Lopez-Beltran | first4 = A. | title = Staging and reporting of urothelial carcinoma of the urinary bladder. | journal = Mod Pathol | volume = 22 Suppl 2 | issue = | pages = S70-95 | month = Jun | year = 2009 | doi = 10.1038/modpathol.2009.1 | PMID = 19494855 | URL = http://www.nature.com/modpathol/journal/v22/n2s/full/modpathol20091a.html }}</ref> | ||
*Breast cancer: not an independent risk factor.<ref name=pmid19436035>{{Cite journal | last1 = Ejlertsen | first1 = B. | last2 = Jensen | first2 = MB. | last3 = Rank | first3 = F. | last4 = Rasmussen | first4 = BB. | last5 = Christiansen | first5 = P. | last6 = Kroman | first6 = N. | last7 = Kvistgaard | first7 = ME. | last8 = Overgaard | first8 = M. | last9 = Toftdahl | first9 = DB. | title = Population-based study of peritumoral lymphovascular invasion and outcome among patients with operable breast cancer. | journal = J Natl Cancer Inst | volume = 101 | issue = 10 | pages = 729-35 | month = May | year = 2009 | doi = 10.1093/jnci/djp090 | PMID = 19436035 }}</ref> | |||
*[[Colorectal carcinoma]]: independent predictor of poorer prognosis.<ref name=pmid20305435>{{Cite journal | last1 = Lim | first1 = SB. | last2 = Yu | first2 = CS. | last3 = Jang | first3 = SJ. | last4 = Kim | first4 = TW. | last5 = Kim | first5 = JH. | last6 = Kim | first6 = JC. | title = Prognostic significance of lymphovascular invasion in sporadic colorectal cancer. | journal = Dis Colon Rectum | volume = 53 | issue = 4 | pages = 377-84 | month = Apr | year = 2010 | doi = 10.1007/DCR.0b013e3181cf8ae5 | PMID = 20305435 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||