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(→Huntington disease: expand a bit) |
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===General=== | ===General=== | ||
*Autosomal dominant inheritance. | *Autosomal dominant inheritance. | ||
*Mutation: | *Mutation in ''Huntington gene'' (HTT):<ref name=pmid20360611>{{cite journal |author=Kumar P, Kalonia H, Kumar A |title=Huntington's disease: pathogenesis to animal models |journal=Pharmacol Rep |volume=62 |issue=1 |pages=1–14 |year=2010 |pmid=20360611 |doi= |url=}}</ref> | ||
**11-34 CAG repeat = normal.<ref name=omim613004>{{OMIM|613004}}</ref> | |||
**>42 CAG repeat = Huntington disease. | |||
Clinical: | |||
*Early onset dementia. | |||
*Involuntary movements (chorea). | |||
===Gross=== | ===Gross=== |
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