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Difference between revisions of "Lymphoma"
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→Lymphoplasmacytic lymphoma
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*Secretes monoclonal IgM. | *Secretes monoclonal IgM. | ||
Clinical:<ref name=Ref_PCPBoD8_325>{{Ref PCPBoD8|325}}</ref> | Note: | ||
*''Waldenström macroglobulinemia'' is a type of lymphoplasmacytic lymphoma<ref name=pmid22507796>{{Cite journal | last1 = Gertz | first1 = MA. | title = Waldenström macroglobulinemia. | journal = Hematology | volume = 17 Suppl 1 | issue = | pages = 112-6 | month = Apr | year = 2012 | doi = 10.1179/102453312X13336169156212 | PMID = 22507796 }}</ref> - it is characterized by: | |||
**''Hyperviscosity syndrome''. | |||
**Bony destruction (seen in [[multiple myeloma]]) is absent.<ref name=Ref_PCPBoD8_325>{{Ref PCPBoD8|325}}</ref> | |||
====Clinical==== | |||
Features:<ref name=Ref_PCPBoD8_325>{{Ref PCPBoD8|325}}</ref> | |||
*Symptoms of blood hyperviscosity (visual impairment, neurologic impairment, bleeding, cryoglobulinemia). | *Symptoms of blood hyperviscosity (visual impairment, neurologic impairment, bleeding, cryoglobulinemia). | ||
*Hemolysis. | *Hemolysis. | ||
*Bence-Jones proteinuria - seen in over half of patients.<ref name=pmid11797112>{{Cite journal | last1 = Kyrtsonis | first1 = MC. | last2 = Vassilakopoulos | first2 = TP. | last3 = Angelopoulou | first3 = MK. | last4 = Siakantaris | first4 = P. | last5 = Kontopidou | first5 = FN. | last6 = Dimopoulou | first6 = MN. | last7 = Boussiotis | first7 = V. | last8 = Gribabis | first8 = A. | last9 = Konstantopoulos | first9 = K. | title = Waldenström's macroglobulinemia: clinical course and prognostic factors in 60 patients. Experience from a single hematology unit. | journal = Ann Hematol | volume = 80 | issue = 12 | pages = 722-7 | month = Dec | year = 2001 | doi = 10.1007/s00277-001-0385-8 | PMID = 11797112 }}</ref> | |||
* | |||
===Microscopic=== | ===Microscopic=== | ||