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:See also: ''[[olfactory neuroblastoma]]''. | :See also: ''[[olfactory neuroblastoma]]''. | ||
===General=== | ===General=== | ||
Laboratory: | Epidemiology: | ||
*Usually paediatric population. | |||
Laboratory findings: | |||
*Increased urine homovanillic acid. | *Increased urine homovanillic acid. | ||
Predictors of a poor prognosis:<ref name=Ref_PCPBoD8_254>{{Ref PCPBoD8|254}}</ref> | |||
* | *High mitotic-karyorrhectic index. | ||
*Lack of schwannian stroma. | |||
*>18 months. | |||
*Near ploidy. | |||
*N-MYC amplification. | |||
*Lymph node spread. | |||
*Distant spread. | |||
Classification: | Classification: | ||
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===Gross=== | ===Gross=== | ||
*~40% | *Typically an abdominal mass. | ||
**~40% arise in the [[adrenal gland]].<ref name=Ref_PCPBoD8_253>{{Ref PCPBoD8|253}}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
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Notes: | Notes: | ||
*The fibrous septa are | *The fibrous septa are especially useful for differentiation from lymphoma. | ||
DDx: | DDx: | ||
*[[Small round cell tumours]]. | *[[Small round cell tumours]]. | ||
**[[Wilms tumour]]. | |||
**Lymphoma. | |||
**[[Hepatoblastoma]]. | |||
Images: | Images: |
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