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Difference between revisions of "Pancreas"
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→Autoimmune pancreatitis
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====Autoimmune pancreatitis==== | ====Autoimmune pancreatitis==== | ||
Histologic subtypes of autoimmune pancreatitis:<ref>URL: [http://path.upmc.edu/cases/case651/dx.html http://path.upmc.edu/cases/case651/dx.html]. Accessed on: 28 January 2012.</ref> | |||
#Lymphoplasmacytic sclerosing pancreatitis (LPSP). | #Lymphoplasmacytic sclerosing pancreatitis (LPSP). | ||
#*IgG4 positive | #*Typically IgG4 positive -- one of the ''[[IgG4-related systemic disease]]s''. | ||
#**IgG4 negative cases reported.<ref name=pmid20824290/><ref name=pmid22466829>{{Cite journal | last1 = Ikeura | first1 = T. | last2 = Takaoka | first2 = M. | last3 = Uchida | first3 = K. | last4 = Shimatani | first4 = M. | last5 = Miyoshi | first5 = H. | last6 = Kusuda | first6 = T. | last7 = Kurishima | first7 = A. | last8 = Fukui | first8 = Y. | last9 = Sumimoto | first9 = K. | title = Autoimmune pancreatitis with histologically proven lymphoplasmacytic sclerosing pancreatitis with granulocytic epithelial lesions. | journal = Intern Med | volume = 51 | issue = 7 | pages = 733-7 | month = | year = 2012 | doi = | PMID = 22466829 }}</ref> | |||
#*Approximately 80% of cases.<ref name=pmid20824290>{{Cite journal | last1 = Kamisawa | first1 = T. | last2 = Takuma | first2 = K. | last3 = Tabata | first3 = T. | last4 = Inaba | first4 = Y. | last5 = Egawa | first5 = N. | last6 = Tsuruta | first6 = K. | last7 = Hishima | first7 = T. | last8 = Sasaki | first8 = T. | last9 = Itoi | first9 = T. | title = Serum IgG4-negative autoimmune pancreatitis. | journal = J Gastroenterol | volume = 46 | issue = 1 | pages = 108-16 | month = Jan | year = 2011 | doi = 10.1007/s00535-010-0317-2 | PMID = 20824290 }}</ref> | |||
#Idiopathic duct-centric chronic pancreatitis (IDCP). | #Idiopathic duct-centric chronic pancreatitis (IDCP). | ||
#*IgG4 negative | #*Typically IgG4 negative. | ||
#*Approximately 20% of cases. | |||
=====Lymphoplasmacytic sclerosing pancreatitis===== | =====Lymphoplasmacytic sclerosing pancreatitis===== | ||
General: | General: | ||
*Serum IgG4 +ve.<ref name=pmid17533077>{{Cite journal | last1 = Krasinskas | first1 = AM. | last2 = Raina | first2 = A. | last3 = Khalid | first3 = A. | last4 = Tublin | first4 = M. | last5 = Yadav | first5 = D. | title = Autoimmune pancreatitis. | journal = Gastroenterol Clin North Am | volume = 36 | issue = 2 | pages = 239-57, vii | month = Jun | year = 2007 | doi = 10.1016/j.gtc.2007.03.015 | PMID = 17533077 }}</ref> | *Serum IgG4 +ve.<ref name=pmid17533077>{{Cite journal | last1 = Krasinskas | first1 = AM. | last2 = Raina | first2 = A. | last3 = Khalid | first3 = A. | last4 = Tublin | first4 = M. | last5 = Yadav | first5 = D. | title = Autoimmune pancreatitis. | journal = Gastroenterol Clin North Am | volume = 36 | issue = 2 | pages = 239-57, vii | month = Jun | year = 2007 | doi = 10.1016/j.gtc.2007.03.015 | PMID = 17533077 }}</ref> | ||
Microscopic: | Microscopic: | ||
*Lymphoplasmacytic infiltrate. | *Lymphoplasmacytic infiltrate. | ||
IHC: | |||
*Plasma cells IgG4 +ve. | |||
===Radiology=== | ===Radiology=== | ||