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Difference between revisions of "Heart valves"
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→Mitral valve prolapse
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*Abbreviated ''MVP''. | *Abbreviated ''MVP''. | ||
===General=== | ===General=== | ||
* | *Classically young women. | ||
*Afflicts ~ 3% of population in the USA.<ref name=Ref_PCPBoD8_296>{{Ref PCPBoD8|296}}</ref> | |||
Clinical: | Clinical: | ||
*Pansystolic murmur. | *Pansystolic murmur. | ||
*+/-Left ventricular hypertrophy - secondary to MVP. | *+/-Left ventricular hypertrophy - secondary to MVP. | ||
Complications:<ref name=Ref_PCPBoD8_296>{{Ref PCPBoD8|296}}</ref> | |||
*[[Infective endocarditis]]. | |||
*Congestive heart failure. | |||
*[[Sudden cardiac death]].<ref name=pmid21133272>{{Cite journal | last1 = Franchitto | first1 = N. | last2 = Bounes | first2 = V. | last3 = Telmon | first3 = N. | last4 = Rougé | first4 = D. | title = Mitral valve prolapse and out-of-hospital sudden death: a case report and literature review. | journal = Med Sci Law | volume = 50 | issue = 3 | pages = 164-7 | month = Jul | year = 2010 | doi = | PMID = 21133272 }}</ref> | |||
*Thromboembolism. | |||
===Gross=== | ===Gross=== | ||
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*Thickening of the valve. | *Thickening of the valve. | ||
*+/-Left ventricular hypertrophy. | *+/-Left ventricular hypertrophy. | ||
Note - location: | |||
*Posterior leaflet pathology more common than anterior leaflet pathology.<ref name=pmid3049284/> | |||
Image: | Image: | ||
| Line 299: | Line 308: | ||
===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid3049284/> | Features:<ref name=pmid3049284/><ref name=Ref_PCPBoD8_296>{{Ref PCPBoD8|296}}</ref> | ||
*Increased thickness of spongiosa | *Increased thickness of spongiosa layer. | ||
* | *Thinning of the fibrosa layer. | ||
*+/-Fibrin deposition. | *+/-Fibrin deposition - atrial aspect. | ||
DDx: | |||
*[[Myxomatous degeneration]].{{fact}} | |||
==Nonbacterial thrombotic endocarditis== | ==Nonbacterial thrombotic endocarditis== | ||