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Difference between revisions of "Germ cell tumours"
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→Yolk sac tumour: more
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==Yolk sac tumour== | ==Yolk sac tumour== | ||
*Abbreviated ''YST''. | |||
*[[AKA]] ''endodermal sinus tumour''. | |||
===General=== | ===General=== | ||
* | *Rare. | ||
*Aggressive - especially extragonadal tumours.<ref name=pmid18767035> | |||
Epidemiology: | |||
*Most common GCT in infants and young boys. | *Most common GCT in infants and young boys. | ||
*Bimodal age distribution:<ref name=pmid18767035>{{Cite journal | last1 = Shah | first1 = JP. | last2 = Kumar | first2 = S. | last3 = Bryant | first3 = CS. | last4 = Ali-Fehmi | first4 = R. | last5 = Malone | first5 = JM. | last6 = Deppe | first6 = G. | last7 = Morris | first7 = RT. | title = A population-based analysis of 788 cases of yolk sac tumors: A comparison of males and females. | journal = Int J Cancer | volume = 123 | issue = 11 | pages = 2671-5 | month = Dec | year = 2008 | doi = 10.1002/ijc.23792 | PMID = 18767035 }}</ref> | |||
**<4 years. | |||
**10-30 years. | |||
Clinical: | |||
*Elevated AFP. | |||
===Gross=== | |||
*White/yellow mucinous infiltrative mass.<ref name=Ref_PCPBoD8_510>{{Ref PCPBoD8|510}}</ref> | |||
===Microscopic=== | ===Microscopic=== | ||
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*[http://www.webpathology.com/image.asp?n=6&Case=34 Hyaline globules (webpathology.com)]. | *[http://www.webpathology.com/image.asp?n=6&Case=34 Hyaline globules (webpathology.com)]. | ||
*[http://path.upmc.edu/cases/case152.html Yolk sac tumour - case 1 - several images (upmc.edu)]. | *[http://path.upmc.edu/cases/case152.html Yolk sac tumour - case 1 - several images (upmc.edu)]. | ||
*[http://path.upmc.edu/cases/case492.html Yolk | *[http://path.upmc.edu/cases/case492.html Yolk sac tumour - case 2 - several images (upmc.edu)]. | ||
*[http://www.moffitt.org/CCJRoot/v11n6/pdf/374.pdf Yolk sac tumour (moffitt.org)].<ref name=pmid15625525>{{Cite journal | last1 = Sesterhenn | first1 = IA. | last2 = Davis | first2 = CJ. | title = Pathology of germ cell tumors of the testis. | journal = Cancer Control | volume = 11 | issue = 6 | pages = 374-87 | month = | year = | doi = | PMID = 15625525 }}</ref> | |||
===IHC=== | ===IHC=== | ||