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Difference between revisions of "Stomach"
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→Gastric adenocarcinoma
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===General=== | ===General=== | ||
Epidemiology: | Epidemiology: | ||
*Prognosis is often poor as it is discovered at a late stage. | *Prognosis is often poor as it is discovered at a late stage. | ||
*Higher prevalence in countries in the far east (e.g. Japan) - thought to be environmental, e.g. diet. | *Higher prevalence in countries in the far east (e.g. Japan) - thought to be environmental, e.g. diet. | ||
Risk factors: | |||
*Associated with helicobacter infections, i.e. [[Helicobacter gastritis]]. | |||
*Alcohol - heavy use.<ref name=pmid21993435>{{Cite journal | last1 = Duell | first1 = EJ. | last2 = Travier | first2 = N. | last3 = Lujan-Barroso | first3 = L. | last4 = Clavel-Chapelon | first4 = F. | last5 = Boutron-Ruault | first5 = MC. | last6 = Morois | first6 = S. | last7 = Palli | first7 = D. | last8 = Krogh | first8 = V. | last9 = Panico | first9 = S. | title = Alcohol consumption and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. | journal = Am J Clin Nutr | volume = 94 | issue = 5 | pages = 1266-75 | month = Nov | year = 2011 | doi = 10.3945/ajcn.111.012351 | PMID = 21993435 }}</ref> | |||
*Genetic syndromes: | |||
**[[Lynch syndrome]]. | |||
**[[Peutz-Jeghers syndrome]]. | |||
Note: | |||
*Possible association with tobacco use - dependent on the study.<ref>{{Cite journal | last1 = Nomura | first1 = A. | last2 = Grove | first2 = JS. | last3 = Stemmermann | first3 = GN. | last4 = Severson | first4 = RK. | title = Cigarette smoking and stomach cancer. | journal = Cancer Res | volume = 50 | issue = 21 | pages = 7084 | month = Nov | year = 1990 | doi = | PMID = 2208177 | URL = http://cancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=2208177}}</ref> | |||
Treatment: | Treatment: | ||