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*Conventional osteosarcoma (high grade). | *Conventional osteosarcoma (high grade). | ||
**Osteoblastic. | **Osteoblastic. | ||
**Fibroblastic | **Fibroblastic. | ||
**Chondroblastic. | |||
**Chondroblastic | *Small cell. | ||
*Small cell | *Telangiectatic. | ||
*Telangiectatic | |||
*Parosteal. | *Parosteal. | ||
*Periosteal. | *Periosteal. | ||
*Low grade central. | *Low grade central. | ||
*High grade surface. | *High grade surface. | ||
*Secondary | *Secondary. | ||
*Gnathic - jaw bones; usually chondroblastic. | |||
*Gnathic - jaw bones; | |||
How to remember: | How to remember: | ||
Line 726: | Line 722: | ||
*Secondary. | *Secondary. | ||
*Telangiectatic. | *Telangiectatic. | ||
=====Chondroblastic osteosarcoma===== | |||
*Chondroid matrix present - may be prominent; osteoid may be a minor component. | |||
*May be confused with [[chondrosarcoma]]. | |||
=====Fibroblastic osteosarcoma===== | |||
*[[Undifferentiated pleomorphic sarcoma]]-like/[[MFH]]-like. | |||
Images: | |||
*[http://path.upmc.edu/cases/case44.html Fibroblastic osteosarcoma (upmc.edu)]. | |||
=====Telangiectatic osteosarcoma===== | |||
*Extremely vascular. | |||
=====Parosteal osteosarcoma===== | |||
*Arise from surface of bone.<ref>{{Ref WHOSTAB|279}}</ref> | |||
*Low grade.<ref name=pmid16896870>{{Cite journal | last1 = Carrle | first1 = D. | last2 = Bielack | first2 = SS. | title = Current strategies of chemotherapy in osteosarcoma. | journal = Int Orthop | volume = 30 | issue = 6 | pages = 445-51 | month = Dec | year = 2006 | doi = 10.1007/s00264-006-0192-x | PMID = 16896870 | PMC = 3172747 | URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172747/?tool=pubmed}}</ref> | |||
=====Small cell osteosarcoma===== | |||
*May mimic (other) [[small round cell tumours]]. | |||
=====Secondary osteosarcoma===== | |||
Arises in the context of something else - causes: | |||
*[[Paget disease of the bone]] (~80% of secondary osteosarcomas) | |||
*Radiation (~15% of secondary osteosarcomas)).<ref>URL: [http://www.rsna.org/REG/publications/rg/afip/privateM/1997/0017/0005/1205/6.htm http://www.rsna.org/REG/publications/rg/afip/privateM/1997/0017/0005/1205/6.htm]. Accessed on: 8 April 2011.</ref> | |||
Images: | |||
*[http://path.upmc.edu/cases/case598.html Secondary osteosarcoma - several images (upmc.edu)]. | |||
==Giant cell tumour of bone== | ==Giant cell tumour of bone== |
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