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Difference between revisions of "Endometrial carcinoma"
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→Subtypes - overview: replace with table
(+mucinous ca of endometrium) |
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==Subtypes - overview== | ==Subtypes - overview== | ||
They are commonly grouped based on clinicopathologic features:<ref name=pmid21309259>{{Cite journal | last1 = Lim | first1 = D. | last2 = Oliva | first2 = E. | title = Nonendometrioid endometrial carcinomas. | journal = Semin Diagn Pathol | volume = 27 | issue = 4 | pages = 241-60 | month = Nov | year = 2010 | doi = | PMID = 21309259 }}</ref> | They are commonly grouped based on clinicopathologic features:<ref name=pmid21309259>{{Cite journal | last1 = Lim | first1 = D. | last2 = Oliva | first2 = E. | title = Nonendometrioid endometrial carcinomas. | journal = Semin Diagn Pathol | volume = 27 | issue = 4 | pages = 241-60 | month = Nov | year = 2010 | doi = | PMID = 21309259 }}</ref><ref name=Ref_GP241>{{Ref GP|241}}</ref> | ||
{| class="wikitable sortable" | |||
!Feature | |||
!Type I | |||
!Type II | |||
|- | |||
|Histologic types | |||
|[[endometrioid endometrial carcinoma]], [[mucinous endometrial carcinoma]] | |||
|[[serous carcinoma of the endometrium]], [[clear cell carcinoma of the endometrium]] | |||
|- | |||
|Clinical <br>characteristics | |||
| premneopausal, estrogen excess, [[endometrial hyperplasia]] | |||
| postmenopausal, no estrogen excess, atrophic endometrium | |||
|- | |||
|Prognosis | |||
| good | |||
| poor | |||
|- | |||
|Genetic <br>abnormalities | |||
| microsatellite instability, PTEN & KRAS mutations | |||
| p53 mutations | |||
|} | |||
==Grading (FIGO)== | ==Grading (FIGO)== | ||