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Difference between revisions of "Neuromuscular pathology"
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→Muscle structure/histology: +table
m (→Stains for muscle biopsies: refs) |
(→Muscle structure/histology: +table) |
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=Muscle structure/histology= | =Muscle structure/histology= | ||
=== | ===Macroscopic to microscopic=== | ||
Organization:<ref>URL: [http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg]. Accessed on: 25 October 2010.</ref> | Organization:<ref>URL: [http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg http://commons.wikimedia.org/wiki/File:Skeletal_muscle.jpg]. Accessed on: 25 October 2010.</ref> | ||
*Muscle - surrounded by epimysium. | *Muscle - surrounded by epimysium. | ||
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{{familytree/end}} | {{familytree/end}} | ||
====List==== | ====List - fibre types==== | ||
Type 1 - [[AKA]] slow twitch: | Type 1 - [[AKA]] slow twitch: | ||
*Predominantly oxidative metabolism, i.e. have lots of mitochondria. | *Predominantly oxidative metabolism, i.e. have lots of mitochondria. | ||
| Line 53: | Line 53: | ||
*Predominantly glycolytic metabolism. | *Predominantly glycolytic metabolism. | ||
Mnemonic '' | Mnemonic for type I fibres ''slow fat red ox'': | ||
*'''Slow''' twitch fibres are lipid rich ('''fat'''), (grossly) more '''red''' (due to mitochondria) and primarily have '''oxidative''' metabolism. | |||
====Table - fibre types==== | |||
<center> | |||
{| class="wikitable sortable" | |||
! Parameter | |||
! Type I | |||
! Type II | |||
|- | |||
| Twitch speed | |||
| slow | |||
| fast | |||
|- | |||
| Colour | |||
| red | |||
| white | |||
|- | |||
| Fat content | |||
| higher | |||
| lower | |||
|- | |||
| ATP production | |||
| oxidative | |||
| anaerobic <br>glycoloysis | |||
|- | |||
| Glycogen | |||
| higher | |||
| lower | |||
|- | |||
| Resistance to fatigue | |||
| higher | |||
| lower | |||
|- | |||
| ATPase quality | |||
| lower | |||
| higher | |||
|- | |||
| Myoglobin | |||
| higher | |||
| lower | |||
|- | |||
| Mitochondria | |||
| higher | |||
| lower | |||
|} | |||
</center> | |||
===Normal findings=== | ===Normal findings=== | ||