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*Meconium contains bile.<ref>{{cite journal |author=Sienko A, Altshuler G |title=Meconium-induced umbilical vascular necrosis in abortuses and fetuses: a histopathologic study for cytokines |journal=Obstet Gynecol |volume=94 |issue=3 |pages=415?0 |year=1999 |month=September |pmid=10472870 |doi= |url=}}</ref> | *Meconium contains bile.<ref>{{cite journal |author=Sienko A, Altshuler G |title=Meconium-induced umbilical vascular necrosis in abortuses and fetuses: a histopathologic study for cytokines |journal=Obstet Gynecol |volume=94 |issue=3 |pages=415?0 |year=1999 |month=September |pmid=10472870 |doi= |url=}}</ref> | ||
==Squamous metaplasia== | ==Squamous metaplasia of the amnion== | ||
*Benign common finding | ===General=== | ||
*Needs to be separated from amnion nodosum.<ref>CS. 7 February 2011.</ref> | *Benign common finding thought to be of no clinical significance.<ref name=Ref_WMSP463>{{Ref WMSP|463}}</ref> | ||
**One case report suggesting an association with chorioamnionitis.<ref>{{Cite journal | last1 = Chew | first1 = RH. | last2 = Silberberg | first2 = BK. | title = Possible association of acute inflammatory exudate in chorioamnionitis and amniotic squamous metaplasia. | journal = Am J Clin Pathol | volume = 93 | issue = 4 | pages = 582-5 | month = Apr | year = 1990 | doi = | PMID = 2321592 }}</ref> | |||
*Needs to be separated from amnion nodosum - '''important'''.<ref>CS. 7 February 2011.</ref> | |||
===Gross=== | |||
*Yellow or white plaques. | |||
DDx: | |||
*[[Amnion nodosum]]. | |||
===Microscopic=== | |||
Features: | |||
*Dense, paucicellular (pink) compact keratin - '''key feature'''. | |||
Image: | Image: |
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