Difference between revisions of "Gynecologic cytopathology"

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===Cytopathology===
===Cytopathology===
Features:
Features:
*Nuclei 3x size of intermediate cell - '''key feature'''. †
#Nuclei 3x size of intermediate cell - '''key feature'''. †
*Irregular nuclear border.
#Irregular nuclear border.
*Chromatin clumping/irregular & granular.
#+/-Perinuclear 'cavity' (clearing).
*+/-Perinuclear 'cavity' (clearing).
#*The best perinuclear halos have a sharp punched-out edge.
**The best perinuclear halos have a sharp punched-out edge.
#Chromatin clumping/irregular & granular.


Note:
Note:
* † Nucleus diameter ~21-24 μm.
* † Nucleus diameter ~21-24 μm.
* In the context of exams: 2 of criteria 1-3 is enough to call LSIL.<ref>Chan, S. 26 April 2012.</ref>


Images:
Images:
*[http://www.flickr.com/photos/moorepix4u2c/1440144102/in/set-72157602113534479/ LSIL ? (flickr.com)].
*[http://www.flickr.com/photos/moorepix4u2c/1440144102/in/set-72157602113534479/ Possible LSIL (flickr.com)].
*[http://commons.wikimedia.org/wiki/File:Low-Grade_SIL_with_HPV_Effect.jpg LSIL with HPV effect (WC)].
*[http://commons.wikimedia.org/wiki/File:Low-Grade_SIL_with_HPV_Effect.jpg LSIL with HPV effect (WC)].


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