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*Infection of the endocardium - often involves the valves (which are covered by endocardium). | *Infection of the endocardium - often involves the valves (which are covered by endocardium). | ||
*Before the time of antibiotics -- 100% fatal. | *Before the time of antibiotics -- 100% fatal. | ||
====Organisms==== | |||
Particular organisms are associated with particular clinical scenarios. | |||
*IV drug user = Staphylococcus aureus. | |||
*No risk factors - normal valve = Streptococcus viridans. | |||
*Prosthetic valves = ''Staphylococcus epidermidis''.<ref>{{Cite journal | last1 = Alonso-Valle | first1 = H. | last2 = Fariñas-Alvarez | first2 = C. | last3 = García-Palomo | first3 = JD. | last4 = Bernal | first4 = JM. | last5 = Martín-Durán | first5 = R. | last6 = Gutiérrez Díez | first6 = JF. | last7 = Revuelta | first7 = JM. | last8 = Fariñas | first8 = MC. | title = Clinical course and predictors of death in prosthetic valve endocarditis over a 20-year period. | journal = J Thorac Cardiovasc Surg | volume = 139 | issue = 4 | pages = 887-93 | month = Apr | year = 2010 | doi = 10.1016/j.jtcvs.2009.05.042 | PMID = 19660339 }}</ref> | |||
====Clinical==== | ====Clinical==== |
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