Difference between revisions of "Gestational trophoblastic disease"

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Line 264: Line 264:
| +/-multinucleation
| +/-multinucleation
| MIB1 high, p63 -ve, CD146 +ve
| MIB1 high, p63 -ve, CD146 +ve
| [[EPS]]
| [[EPS]], [[PSTT]]
| Other?
| Other?
| [http://www.webpathology.com/case.asp?case=588 (webpathology.com)]
| [http://www.webpathology.com/case.asp?case=588 (webpathology.com)]
Line 278: Line 278:
| [[Choriocarcinoma]]
| [[Choriocarcinoma]]
| polygonal cells with clear cytoplasm (cytotrophoblasts)
| polygonal cells with clear cytoplasm (cytotrophoblasts)
| multinucleated cells with smudged nuclei (syncytiotrophoblasts), usu. '''no''' [[chorionic villi]]
| multinucleated cells with smudged nuclei (syncytiotrophoblasts), '''no''' [[chorionic villi]]
| beta-hCG +ve, p63 +ve
| beta-hCG +ve, p63 +ve
| DDx?
| [[invasive hydatidiform mole]], [[PSTT]]
| elevated beta-hCG (serum); '''not''' intermediate trophoblast derived.
| elevated beta-hCG (serum); '''not''' intermediate trophoblast derived.
| [http://www.webpathology.com/image.asp?case=36&n=1 (webpathology.com)]
| [http://www.webpathology.com/image.asp?case=36&n=1 (webpathology.com)]
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