Difference between revisions of "Stomach"

Stomach (view source)

428 bytes added , 20:36, 20 April 2012

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 ==Pernicious anemia==
 ===General===
-*Gastric atrophy.
+*Pathology: loss of parietal cells, gastric atrophy, [[macrocytic anemia]].
-*Loss of parietal cells.
+*Etiology: autoimmune.
-*Intrinsic factor antibodies present in serum.
-**Intrinsic factor -- absorbs vitamin B12.
+Diagnosis based serology for antibodies to:<ref name=pmid12643357>{{Cite journal  | last1 = Oh | first1 = R. | last2 = Brown | first2 = DL. | title = Vitamin B12 deficiency. | journal = Am Fam Physician | volume = 67 | issue = 5 | pages = 979-86 | month = Mar | year = 2003 | doi =  | PMID = 12643357 }}</ref>
-*Macrocytic [[anemia]].
+*Parietal cells.
+*Iintrinsic factor.
+Note:
+*Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride'', i.e. stomach acid.
 ===Microscopic===