Difference between revisions of "Non-malignant skin disease"

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(PBoD, WMSP)
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==Lichen simplex chronicus==
==Lichen simplex chronicus==
===Histology===
===General===
Key features:<ref name=Ref_PBoD1065-6>{{Ref PBoD|1065-6}}</ref>
*Variant of ''spongiotic dermatitis''.<ref name=Ref_DCHH296>{{Ref DCHH|296}}</ref>
 
Etiology:<ref>URL: [http://emedicine.medscape.com/article/1123423-overview http://emedicine.medscape.com/article/1123423-overview]. Accessed on: 20 August 2010.</ref>
*Pruritus -> mechanical trauma -> lichenification (thickened/leathery<ref>URL: [http://www.medterms.com/script/main/art.asp?articlekey=10131 http://www.medterms.com/script/main/art.asp?articlekey=10131]. Accessed on: 20 August 2010.</ref>.
 
===Microscopic===
Features:<ref name=Ref_PBoD1065-6>{{Ref PBoD|1065-6}}</ref>
*Acanthosis (epithelial thickening).  
*Acanthosis (epithelial thickening).  
*Hyperkeratosis.
*Hyperkeratosis.
Other features:<ref>URL: [http://emedicine.medscape.com/article/1123423-diagnosis http://emedicine.medscape.com/article/1123423-diagnosis]. Accessed on: 20 August 2010.</ref>
*Spongiosis (epidermal intercellular edema -- cells appear to have a clear halo around 'em).
*Parakeratosis = retention of nuclei in the stratum corneum.


==Seborrheic keratosis==
==Seborrheic keratosis==
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