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Difference between revisions of "Vascular tumours"
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→Epithelioid hemangioendothelioma
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===Microscopic=== | ===Microscopic=== | ||
Features:<ref name=pmid20165548>{{Cite journal | last1 = Gupta | first1 = R. | last2 = Mathur | first2 = SR. | last3 = Gupta | first3 = SD. | last4 = Durgapal | first4 = P. | last5 = Iyer | first5 = VK. | last6 = Das | first6 = CJ. | last7 = Shalimar | first7 = SK. | last8 = Acharya | first8 = . | title = Hepatic epithelioid hemangioendothelioma: A diagnostic pitfall in aspiration cytology. | journal = Cytojournal | volume = 6 | issue = | pages = 25 | month = | year = 2010 | doi = 10.4103/1742-6413.58951 | PMID = 20165548 | URL = http://www.biomedsearch.com/nih/Hepatic-epithelioid-hemangioendothelioma-diagnostic-pitfall/20165548.html }}</ref> | Features:<ref name=pmid20165548>{{Cite journal | last1 = Gupta | first1 = R. | last2 = Mathur | first2 = SR. | last3 = Gupta | first3 = SD. | last4 = Durgapal | first4 = P. | last5 = Iyer | first5 = VK. | last6 = Das | first6 = CJ. | last7 = Shalimar | first7 = SK. | last8 = Acharya | first8 = . | title = Hepatic epithelioid hemangioendothelioma: A diagnostic pitfall in aspiration cytology. | journal = Cytojournal | volume = 6 | issue = | pages = 25 | month = | year = 2010 | doi = 10.4103/1742-6413.58951 | PMID = 20165548 | URL = http://www.biomedsearch.com/nih/Hepatic-epithelioid-hemangioendothelioma-diagnostic-pitfall/20165548.html }}</ref> | ||
*Large epithelioid perivascular cells | *Large epithelioid perivascular cells with: | ||
**Abundant pale eosinophilic cytoplasm. | **Abundant pale eosinophilic cytoplasm. | ||
**Cytoplasmic vacuolation (some cells) - [[AKA]] "blister cells" - '''key feature'''. | **Cytoplasmic vacuolation (some cells) - [[AKA]] "blister cells" - '''key feature'''. | ||
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**Vesicular nucleus with prominent nucleolus in some cells. | **Vesicular nucleus with prominent nucleolus in some cells. | ||
*Tuft-like projections into capillaries. | *Tuft-like projections into capillaries. | ||
*Tumour cells may be in well-circumscribed paucicellular nodules ''or'' more cellular poorly formed aggregates. | |||
DDx: | DDx: | ||
*[[Angiosarcoma]], epithelioid. | *[[Angiosarcoma]], epithelioid. | ||
*[[Hemangioma]]. | *[[Hemangioma]]. | ||
Images: | Images: | ||
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*[http://www.flickr.com/photos/pulmonary_pathology/5600772691/in/photostream/ Epithelioid hemangioendothelioma - low mag. (flickr.com/Rosen)]. | *[http://www.flickr.com/photos/pulmonary_pathology/5600772691/in/photostream/ Epithelioid hemangioendothelioma - low mag. (flickr.com/Rosen)]. | ||
*[http://www.flickr.com/photos/pulmonary_pathology/5601354962/ Epithelioid hemangioendothelioma - high mag. (flickr.com/Rosen)]. | *[http://www.flickr.com/photos/pulmonary_pathology/5601354962/ Epithelioid hemangioendothelioma - high mag. (flickr.com/Rosen)]. | ||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802170854495 Epithelioid hemangioendothelioma (surgicalpathologyatlas.com)]. | |||
===IHC=== | ===IHC=== | ||