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(→Basic pathologic DDx of malignancy: update tree) |
(→Classification of granuloma: formating, memory device) |
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===Classification of granuloma=== | ===Classification of granuloma=== | ||
====Histologic classification==== | |||
#Necrosing (also ''caseating''). | |||
#*More likely to be infectious. | |||
#*Examples: Tuberculosis (TB). | |||
#Non-necrosing. | |||
#*Less likely to be infectious. | |||
#*Examples: Crohn's disease, sarcoidosis, drug reaction. | |||
Whether necrosis is present in a granuloma is affected by the immune function, e.g. a HIV/AIDS patient may have non-necrosing granulomata due to TB. | Whether necrosis is present in a granuloma is affected by the immune function, e.g. a HIV/AIDS patient may have non-necrosing granulomata due to TB. | ||
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*Infectious non-necrosing infections: Mycobacterium avium complex (MAC), cryptococcus, immunosuppressed individual.<ref name=pmid17257125/> | *Infectious non-necrosing infections: Mycobacterium avium complex (MAC), cryptococcus, immunosuppressed individual.<ref name=pmid17257125/> | ||
Etiologic classification | ====Etiologic classification==== | ||
#Infectious, e.g. tuberculosis, MAC, fungal infection. | #Infectious, e.g. tuberculosis, MAC, fungal infection. | ||
#Neoplastic, e.g. seminoma. | #Neoplastic, e.g. seminoma. | ||
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#Drug reaction. | #Drug reaction. | ||
#Idiopathic, e.g. sarcoidosis. | #Idiopathic, e.g. sarcoidosis. | ||
Memory device: ''DNF AAII'' = drug reaction, neoplasm, foreign body, allergy, autoimmune, idiopathic infection. | |||
===Lung granulomata=== | ===Lung granulomata=== |
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