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Difference between revisions of "Mesothelial cytopathology"
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→Specific diagnoses: +rheumatoid pleuritis
(→Specific diagnoses: +rheumatoid pleuritis) |
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| Line 68: | Line 68: | ||
*Large clusters of cells, e.g. 150+ micrometres. | *Large clusters of cells, e.g. 150+ micrometres. | ||
=Specific diagnoses= | =Specific diagnoses - benign= | ||
==Eosinophilic pleuritis== | |||
===General=== | |||
This has a large DDx: | |||
*Trauma with air in the pleural cavity. | |||
**Repeated tap in the context of pneumothorax. | |||
*[[Pulmonary infarct]]. | |||
*[[Pneumonia]]. | |||
*Parasitic infections. | |||
*[[Hodgkin lymphoma]]. | |||
*Idiopathic - most common cause. | |||
===Cytology=== | |||
Features: | |||
*Eosinophils >10%. | |||
==Rheumatoid pleuritis== | |||
===General=== | |||
*History of [[rheumatoid arthritis]]. | |||
*Cytologic appearance considered to be ''pathognomonic''.<ref name=pmid2197838/> | |||
===Cytology=== | |||
Features:<ref name=pmid2197838>{{Cite journal | last1 = Naylor | first1 = B. | title = The pathognomonic cytologic picture of rheumatoid pleuritis. The 1989 Maurice Goldblatt Cytology award lecture. | journal = Acta Cytol | volume = 34 | issue = 4 | pages = 465-73 | month = | year = | doi = | PMID = 2197838 }}</ref> | |||
*Large (single) multinucleated cells - classically spindled. | |||
**May have epithelioid morphology. | |||
*Necrotic debris - fluffy orange-to-blue crap. | |||
Note: | |||
*Necrotizing granulomatous inflammation. | |||
=Specific diagnoses - malignant= | |||
==Malignant mesothelioma== | ==Malignant mesothelioma== | ||
{{Main|Malignant mesothelioma}} | {{Main|Malignant mesothelioma}} | ||
| Line 140: | Line 170: | ||
==Breast carcinoma in fluid== | ==Breast carcinoma in fluid== | ||
===Cytology=== | ===Cytology=== | ||
Breast adenocarcinoma in fluid - features:<ref name=Ref_APBR675>{{Ref APBR|675}}</ref> | Breast adenocarcinoma in fluid - features:<ref name=Ref_APBR675>{{Ref APBR|675}}</ref> | ||
| Line 203: | Line 232: | ||
*CA-125 +ve. | *CA-125 +ve. | ||
*D2-40 +ve. | *D2-40 +ve. | ||
=See also= | =See also= | ||