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Difference between revisions of "Pulmonary pathology"
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Tumours of the lung are dealt with in [[lung tumours]] article. Lung [[cytopathology]] is dealt with in the ''[[pulmonary cytopathology]]'' article. | Tumours of the lung are dealt with in [[lung tumours]] article. Lung [[cytopathology]] is dealt with in the ''[[pulmonary cytopathology]]'' article. | ||
=Lung specimens= | |||
*Ultrasound-guided needle core biopsy - for peripheral lesions. | *Ultrasound-guided needle core biopsy - for peripheral lesions. | ||
*Transbronchial biopsy - for central lesions. | *Transbronchial biopsy - for central lesions. | ||
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*Explantation - in the context of [[lung transplantation pathology|lung transplantation]] - done for [[cystic fibrosis]] [[Idiopathic pulmonary fibrosis]] and other causes. | *Explantation - in the context of [[lung transplantation pathology|lung transplantation]] - done for [[cystic fibrosis]] [[Idiopathic pulmonary fibrosis]] and other causes. | ||
=Basic approach= | |||
All lung pathology can be grouped into one of six categories (as per Leslie). The radiology directly correlates to the pathologic grouping, except that ''air space disease'' encompasses three pathologic categories (ALI, CCI, AFD). | All lung pathology can be grouped into one of six categories (as per Leslie). The radiology directly correlates to the pathologic grouping, except that ''air space disease'' encompasses three pathologic categories (ALI, CCI, AFD). | ||
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*Vessels - thickening? | *Vessels - thickening? | ||
=Normal histology= | |||
===Cells=== | ===Cells=== | ||
Common: | Common: | ||
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*Smoker's macrophages = brown-pigmented macrophages - assoc. with smoking.<ref name=Ref_PPP236>{{Ref PPP|236}}</ref> | *Smoker's macrophages = brown-pigmented macrophages - assoc. with smoking.<ref name=Ref_PPP236>{{Ref PPP|236}}</ref> | ||
=Detail articles= | |||
==Malignancy - lung cancer== | ==Malignancy - lung cancer== | ||
{{main|Lung cancer}} | {{main|Lung cancer}} | ||
This | This pretty much always comes to the pathologist. | ||
==Medical lung disease== | ==Medical lung disease== | ||
{{main|Medical lung disease}} | {{main|Medical lung disease}} | ||
There are separate articles for: | |||
*[[Pneumonia]]. | |||
*[[Diffuse lung diseases]], e.g. ''[[usual interstitial pneumonia]]''. | |||
*[[Pulmonary hypertension]]. | |||
==Lung transplant pathology== | ==Lung transplant pathology== | ||
{{Main|Lung transplant pathology}} | {{Main|Lung transplant pathology}} | ||
=Specific diagnoses= | |||
==Bronchogenic cyst== | ==Bronchogenic cyst== | ||
===General=== | ===General=== | ||
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*[http://www.pathologyoutlines.com/topic/lungnontumorBPD.html BPD (pathologyoutlines.com)]. | *[http://www.pathologyoutlines.com/topic/lungnontumorBPD.html BPD (pathologyoutlines.com)]. | ||
==See also | ==Pulmonary infarct== | ||
*[[AKA]] ''lung infarct'', ''lung infarction'', ''pulmonary infarction''. | |||
===General=== | |||
*Uncommon because of the dual blood supply (systemic via the bronchial arteries, pulmonary via the pulmonary arteries). | |||
===Gross=== | |||
*Wedge-shaped and at the lung periphery. | |||
**In a histologic section lung infarcts are triangular: | |||
***Base of triangle on the pleural aspect. | |||
***Point furthest from the pleura close to the compromised artery that lead to infarction. | |||
===Microscopic=== | |||
Features: | |||
*[[Necrosis]] of alveolar walls - loss of nuclei. | |||
*Alveolar hemorrhage. | |||
Image: | |||
*[http://commons.wikimedia.org/wiki/File:Pulmonary_infarct_intermed_mag.jpg Pulmonayr infarct - low mag. (WC)]. | |||
=See also= | |||
*[[Medical lung disease]]. | *[[Medical lung disease]]. | ||
*[[Thyroid]]. | *[[Thyroid]]. | ||
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*[[Heart]]. | *[[Heart]]. | ||
=References= | |||
{{reflist|2}} | {{reflist|2}} | ||
=External links= | |||
*[http://www.flickr.com/photos/pulmonary_pathology/with/5613145721/ Pulmonary pathology (flickr.com)]. | *[http://www.flickr.com/photos/pulmonary_pathology/with/5613145721/ Pulmonary pathology (flickr.com)]. | ||
[[Category:Pulmonary pathology]] | [[Category:Pulmonary pathology]] | ||